Pre-intervention triage incorporating perfusion imaging improves outcomes in patients undergoing endovascular stroke therapy

A comparison with the device trials

Ansaar T. Rai, Karthikram Raghuram, Jennifer Domico, Gerald Hobbs, Jeffrey Carpenter

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Objectives Endovascular therapy of acute ischemic stroke is evolving towards thrombectomy devices for vessel recanalization. High rates of revascularization have been reported in stroke device trials. However, the discrepancy between recanalization and outcomes raises the question whether patients with irreversible ischemic injury are being exposed to these interventions. This study evaluated a triage methodology that incorporates perfusion imaging against previous device trials that treated all patients within a certain time frame. Methods 99 consecutive patients were identified with anterior circulation strokes who had undergone endovascular therapy. All patients had a baseline NIHSS score ≥8 and had undergone pre-intervention CT perfusion. Rates of recanalization and functional outcomes were compared with the MERCI, Multi-MERCI and Penumbra trials. Results This study's recanalization rate of 55.6% is not significantly different from the 46% for MERCI (p=0.15) and 68% for Multi-MERCI (p=0.08) but was significantly lower than the 82% for the Penumbra trial (p

Original languageEnglish (US)
Pages (from-to)121-127
Number of pages7
JournalJournal of NeuroInterventional Surgery
Volume5
Issue number2
DOIs
StatePublished - Mar 2013
Externally publishedYes

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Perfusion Imaging
Triage
Stroke
Equipment and Supplies
Thrombectomy
Therapeutics
Perfusion
Wounds and Injuries

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Pre-intervention triage incorporating perfusion imaging improves outcomes in patients undergoing endovascular stroke therapy : A comparison with the device trials. / Rai, Ansaar T.; Raghuram, Karthikram; Domico, Jennifer; Hobbs, Gerald; Carpenter, Jeffrey.

In: Journal of NeuroInterventional Surgery, Vol. 5, No. 2, 03.2013, p. 121-127.

Research output: Contribution to journalArticle

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