Prediction and timing of tracheostomy in patients with infratentorial lesions requiring mechanical ventilatory support

Adrian I. Qureshi, Jose I. Suarez, Parag D. Parekh, Anish Bhardwaj

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Objectives: To determine the frequency and predictors of successful extubations and tracheostomy in patients with infratentorial lesions requiring mechanical ventilation and to determine the optimal time for tracheostomy based on probability of successful extubation and in-hospital survival according to the duration of translaryngeal intubation. Design: Retrospective chart review. Settings. A neurocritical care unit at a university hospital. Patients: A total of 69 patients with infratentorial lesions who were mechanically ventilated during their intensive care unit stay. Measurements and Main Results: Of the 69 patients who were mechanically ventilated, 23 (33%) were successfully extubated. In logistic regression analysis, both the presence of a Glasgow Coma Scale score >7 at time of intubation (odds ratio, 4.8; 95% confidence interval, 1.2-21.7) and the absence of brainstem deficits (odds ratio, 4.3; 95% confidence interval, 1.3- 16.7), were independently associated with successful extubation. After extubation, 11 patients were reintubated; seven were reintubated within the same day because of poor control over secretions, airway spasm, or hypoventilation. Tracheostomy was performed in 23 (33%) patients, of whom 19 were successfully weaned off mechanical ventilatory support over a mean period of 3.7 ± 4.0 days after tracheostomy. Patients undergoing tracheostomy had a significantly longer intensive care unit stay (19.1 ± 9.0 vs. 8.7 ± 6.6 days, p < .01) and total hospital stay (34.8 ± 18.7 vs. 20.1 ± 9.9 days, p < .81) compared with patients who were successfully extubatad. The probability of successful extubation or death before extubation or tracheostomy was 67% on the day of intubation, which decreased to 5.8% after translaryngeal intubation for >8 days. Conclusions: An aggressive policy toward tracheostomy is justified based on the low frequency of successful extubations and high frequency of extubation failures and tracheostomies in patients with infratentorial lesions. The decision regarding tracheostomy should be made on day 8 of mechanical ventilatory support because of the low probability of subsequent extubation or in-hospital death.

Original languageEnglish (US)
Pages (from-to)1383-1387
Number of pages5
JournalCritical Care Medicine
Volume28
Issue number5
StatePublished - 2000
Externally publishedYes

Fingerprint

Tracheostomy
Intubation
Intensive Care Units
Odds Ratio
Confidence Intervals
Hypoventilation
Glasgow Coma Scale
Spasm
Artificial Respiration
Brain Stem
Logistic Models
Regression Analysis
Survival

Keywords

  • Extubation
  • Glasgow coma scale
  • Infratentorial lesions
  • Intubation
  • Mechanical ventilatory support
  • Tracheostomy

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Prediction and timing of tracheostomy in patients with infratentorial lesions requiring mechanical ventilatory support. / Qureshi, Adrian I.; Suarez, Jose I.; Parekh, Parag D.; Bhardwaj, Anish.

In: Critical Care Medicine, Vol. 28, No. 5, 2000, p. 1383-1387.

Research output: Contribution to journalArticle

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abstract = "Objectives: To determine the frequency and predictors of successful extubations and tracheostomy in patients with infratentorial lesions requiring mechanical ventilation and to determine the optimal time for tracheostomy based on probability of successful extubation and in-hospital survival according to the duration of translaryngeal intubation. Design: Retrospective chart review. Settings. A neurocritical care unit at a university hospital. Patients: A total of 69 patients with infratentorial lesions who were mechanically ventilated during their intensive care unit stay. Measurements and Main Results: Of the 69 patients who were mechanically ventilated, 23 (33{\%}) were successfully extubated. In logistic regression analysis, both the presence of a Glasgow Coma Scale score >7 at time of intubation (odds ratio, 4.8; 95{\%} confidence interval, 1.2-21.7) and the absence of brainstem deficits (odds ratio, 4.3; 95{\%} confidence interval, 1.3- 16.7), were independently associated with successful extubation. After extubation, 11 patients were reintubated; seven were reintubated within the same day because of poor control over secretions, airway spasm, or hypoventilation. Tracheostomy was performed in 23 (33{\%}) patients, of whom 19 were successfully weaned off mechanical ventilatory support over a mean period of 3.7 ± 4.0 days after tracheostomy. Patients undergoing tracheostomy had a significantly longer intensive care unit stay (19.1 ± 9.0 vs. 8.7 ± 6.6 days, p < .01) and total hospital stay (34.8 ± 18.7 vs. 20.1 ± 9.9 days, p < .81) compared with patients who were successfully extubatad. The probability of successful extubation or death before extubation or tracheostomy was 67{\%} on the day of intubation, which decreased to 5.8{\%} after translaryngeal intubation for >8 days. Conclusions: An aggressive policy toward tracheostomy is justified based on the low frequency of successful extubations and high frequency of extubation failures and tracheostomies in patients with infratentorial lesions. The decision regarding tracheostomy should be made on day 8 of mechanical ventilatory support because of the low probability of subsequent extubation or in-hospital death.",
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T1 - Prediction and timing of tracheostomy in patients with infratentorial lesions requiring mechanical ventilatory support

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AU - Suarez, Jose I.

AU - Parekh, Parag D.

AU - Bhardwaj, Anish

PY - 2000

Y1 - 2000

N2 - Objectives: To determine the frequency and predictors of successful extubations and tracheostomy in patients with infratentorial lesions requiring mechanical ventilation and to determine the optimal time for tracheostomy based on probability of successful extubation and in-hospital survival according to the duration of translaryngeal intubation. Design: Retrospective chart review. Settings. A neurocritical care unit at a university hospital. Patients: A total of 69 patients with infratentorial lesions who were mechanically ventilated during their intensive care unit stay. Measurements and Main Results: Of the 69 patients who were mechanically ventilated, 23 (33%) were successfully extubated. In logistic regression analysis, both the presence of a Glasgow Coma Scale score >7 at time of intubation (odds ratio, 4.8; 95% confidence interval, 1.2-21.7) and the absence of brainstem deficits (odds ratio, 4.3; 95% confidence interval, 1.3- 16.7), were independently associated with successful extubation. After extubation, 11 patients were reintubated; seven were reintubated within the same day because of poor control over secretions, airway spasm, or hypoventilation. Tracheostomy was performed in 23 (33%) patients, of whom 19 were successfully weaned off mechanical ventilatory support over a mean period of 3.7 ± 4.0 days after tracheostomy. Patients undergoing tracheostomy had a significantly longer intensive care unit stay (19.1 ± 9.0 vs. 8.7 ± 6.6 days, p < .01) and total hospital stay (34.8 ± 18.7 vs. 20.1 ± 9.9 days, p < .81) compared with patients who were successfully extubatad. The probability of successful extubation or death before extubation or tracheostomy was 67% on the day of intubation, which decreased to 5.8% after translaryngeal intubation for >8 days. Conclusions: An aggressive policy toward tracheostomy is justified based on the low frequency of successful extubations and high frequency of extubation failures and tracheostomies in patients with infratentorial lesions. The decision regarding tracheostomy should be made on day 8 of mechanical ventilatory support because of the low probability of subsequent extubation or in-hospital death.

AB - Objectives: To determine the frequency and predictors of successful extubations and tracheostomy in patients with infratentorial lesions requiring mechanical ventilation and to determine the optimal time for tracheostomy based on probability of successful extubation and in-hospital survival according to the duration of translaryngeal intubation. Design: Retrospective chart review. Settings. A neurocritical care unit at a university hospital. Patients: A total of 69 patients with infratentorial lesions who were mechanically ventilated during their intensive care unit stay. Measurements and Main Results: Of the 69 patients who were mechanically ventilated, 23 (33%) were successfully extubated. In logistic regression analysis, both the presence of a Glasgow Coma Scale score >7 at time of intubation (odds ratio, 4.8; 95% confidence interval, 1.2-21.7) and the absence of brainstem deficits (odds ratio, 4.3; 95% confidence interval, 1.3- 16.7), were independently associated with successful extubation. After extubation, 11 patients were reintubated; seven were reintubated within the same day because of poor control over secretions, airway spasm, or hypoventilation. Tracheostomy was performed in 23 (33%) patients, of whom 19 were successfully weaned off mechanical ventilatory support over a mean period of 3.7 ± 4.0 days after tracheostomy. Patients undergoing tracheostomy had a significantly longer intensive care unit stay (19.1 ± 9.0 vs. 8.7 ± 6.6 days, p < .01) and total hospital stay (34.8 ± 18.7 vs. 20.1 ± 9.9 days, p < .81) compared with patients who were successfully extubatad. The probability of successful extubation or death before extubation or tracheostomy was 67% on the day of intubation, which decreased to 5.8% after translaryngeal intubation for >8 days. Conclusions: An aggressive policy toward tracheostomy is justified based on the low frequency of successful extubations and high frequency of extubation failures and tracheostomies in patients with infratentorial lesions. The decision regarding tracheostomy should be made on day 8 of mechanical ventilatory support because of the low probability of subsequent extubation or in-hospital death.

KW - Extubation

KW - Glasgow coma scale

KW - Infratentorial lesions

KW - Intubation

KW - Mechanical ventilatory support

KW - Tracheostomy

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