Premorbid personality assessments of first onset of major depression

R. M A Hirschfeld, G. L. Klerman, P. Lavori, M. B. Keller, P. Griffith, W. Coryell

Research output: Contribution to journalArticle

345 Citations (Scopus)

Abstract

This is a report on personality traits associated with the first onset of major depression in a sample of high-risk subjects. The subjects are the first-degree relatives, spouses, and their controls of patients with affective disorders. None of these subjects had any history of mental disorder as of their initial evaluation. In the subsequent six years, 29 subjects had a first onset of major depression. These first onset subjects were compared with 370 subjects who continued to be free of illness during the six-year follow-up. Personality traits were assessed at the initial evaluation (ie, before the onset of depression in subjects with first onset) by means of scales from five self-report inventories. Lower emotional strength and resiliency significantly differentiated the first onset from the never ill group; overall differences were not found on measures of interpersonal dependency or extraversion. Age was a significant predictor of first onset, both alone (younger age predicted first onsets) and in interaction with personality measures. Among younger subjects (17 to 30 years of age), personality variables did not significantly discriminate between the two comparison groups. Among older subjects (31 to 41 years of age), however, decreased emotional strength, increased interpersonal dependency, and increased thoughtfulness were associated with first onset of depression.

Original languageEnglish (US)
Pages (from-to)345-350
Number of pages6
JournalArchives of General Psychiatry
Volume46
Issue number4
StatePublished - 1989

Fingerprint

Personality Assessment
Personality
Depression
Mood Disorders
Spouses
Mental Disorders
Self Report
Equipment and Supplies
Dependency (Psychology)

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Hirschfeld, R. M. A., Klerman, G. L., Lavori, P., Keller, M. B., Griffith, P., & Coryell, W. (1989). Premorbid personality assessments of first onset of major depression. Archives of General Psychiatry, 46(4), 345-350.

Premorbid personality assessments of first onset of major depression. / Hirschfeld, R. M A; Klerman, G. L.; Lavori, P.; Keller, M. B.; Griffith, P.; Coryell, W.

In: Archives of General Psychiatry, Vol. 46, No. 4, 1989, p. 345-350.

Research output: Contribution to journalArticle

Hirschfeld, RMA, Klerman, GL, Lavori, P, Keller, MB, Griffith, P & Coryell, W 1989, 'Premorbid personality assessments of first onset of major depression', Archives of General Psychiatry, vol. 46, no. 4, pp. 345-350.
Hirschfeld RMA, Klerman GL, Lavori P, Keller MB, Griffith P, Coryell W. Premorbid personality assessments of first onset of major depression. Archives of General Psychiatry. 1989;46(4):345-350.
Hirschfeld, R. M A ; Klerman, G. L. ; Lavori, P. ; Keller, M. B. ; Griffith, P. ; Coryell, W. / Premorbid personality assessments of first onset of major depression. In: Archives of General Psychiatry. 1989 ; Vol. 46, No. 4. pp. 345-350.
@article{a31cfa869e204f93b2759d7bf922b0da,
title = "Premorbid personality assessments of first onset of major depression",
abstract = "This is a report on personality traits associated with the first onset of major depression in a sample of high-risk subjects. The subjects are the first-degree relatives, spouses, and their controls of patients with affective disorders. None of these subjects had any history of mental disorder as of their initial evaluation. In the subsequent six years, 29 subjects had a first onset of major depression. These first onset subjects were compared with 370 subjects who continued to be free of illness during the six-year follow-up. Personality traits were assessed at the initial evaluation (ie, before the onset of depression in subjects with first onset) by means of scales from five self-report inventories. Lower emotional strength and resiliency significantly differentiated the first onset from the never ill group; overall differences were not found on measures of interpersonal dependency or extraversion. Age was a significant predictor of first onset, both alone (younger age predicted first onsets) and in interaction with personality measures. Among younger subjects (17 to 30 years of age), personality variables did not significantly discriminate between the two comparison groups. Among older subjects (31 to 41 years of age), however, decreased emotional strength, increased interpersonal dependency, and increased thoughtfulness were associated with first onset of depression.",
author = "Hirschfeld, {R. M A} and Klerman, {G. L.} and P. Lavori and Keller, {M. B.} and P. Griffith and W. Coryell",
year = "1989",
language = "English (US)",
volume = "46",
pages = "345--350",
journal = "JAMA Psychiatry",
issn = "2168-622X",
publisher = "American Medical Association",
number = "4",

}

TY - JOUR

T1 - Premorbid personality assessments of first onset of major depression

AU - Hirschfeld, R. M A

AU - Klerman, G. L.

AU - Lavori, P.

AU - Keller, M. B.

AU - Griffith, P.

AU - Coryell, W.

PY - 1989

Y1 - 1989

N2 - This is a report on personality traits associated with the first onset of major depression in a sample of high-risk subjects. The subjects are the first-degree relatives, spouses, and their controls of patients with affective disorders. None of these subjects had any history of mental disorder as of their initial evaluation. In the subsequent six years, 29 subjects had a first onset of major depression. These first onset subjects were compared with 370 subjects who continued to be free of illness during the six-year follow-up. Personality traits were assessed at the initial evaluation (ie, before the onset of depression in subjects with first onset) by means of scales from five self-report inventories. Lower emotional strength and resiliency significantly differentiated the first onset from the never ill group; overall differences were not found on measures of interpersonal dependency or extraversion. Age was a significant predictor of first onset, both alone (younger age predicted first onsets) and in interaction with personality measures. Among younger subjects (17 to 30 years of age), personality variables did not significantly discriminate between the two comparison groups. Among older subjects (31 to 41 years of age), however, decreased emotional strength, increased interpersonal dependency, and increased thoughtfulness were associated with first onset of depression.

AB - This is a report on personality traits associated with the first onset of major depression in a sample of high-risk subjects. The subjects are the first-degree relatives, spouses, and their controls of patients with affective disorders. None of these subjects had any history of mental disorder as of their initial evaluation. In the subsequent six years, 29 subjects had a first onset of major depression. These first onset subjects were compared with 370 subjects who continued to be free of illness during the six-year follow-up. Personality traits were assessed at the initial evaluation (ie, before the onset of depression in subjects with first onset) by means of scales from five self-report inventories. Lower emotional strength and resiliency significantly differentiated the first onset from the never ill group; overall differences were not found on measures of interpersonal dependency or extraversion. Age was a significant predictor of first onset, both alone (younger age predicted first onsets) and in interaction with personality measures. Among younger subjects (17 to 30 years of age), personality variables did not significantly discriminate between the two comparison groups. Among older subjects (31 to 41 years of age), however, decreased emotional strength, increased interpersonal dependency, and increased thoughtfulness were associated with first onset of depression.

UR - http://www.scopus.com/inward/record.url?scp=0024517348&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024517348&partnerID=8YFLogxK

M3 - Article

C2 - 2649038

AN - SCOPUS:0024517348

VL - 46

SP - 345

EP - 350

JO - JAMA Psychiatry

JF - JAMA Psychiatry

SN - 2168-622X

IS - 4

ER -