Presence of respiratory viruses in middle ear fluids and nasal wash specimens from children with acute otitis media

T. Chonmaitree, V. M. Howie, A. L. Truant

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

During a 28-month period, 84 children with acute otitis media were studied by viral and bacterial cultures of middle ear fluid and viral cultures of nasal lavage fluid. Viruses were isolated from the middle ear fluid of 17 (20%) patients. Evidence of viral infection was demonstrated by positive viral cultures of middle ear fluid and/or nasal lavage fluid in 33 (39%) patients. Rhinovirus in one patient and influenza b virus in another were the only pathogens isolated. Influenza virus, enterovirus, and rhinovirus were the most common viruses found in middle ear fluids. Parainfluenza virus, adenovirus, and respiratory syncytial virus were found less often. In 82% of cases, the virus isolated from middle ear fluid was also isolated from nasal lavage fluid, but only 44% of viruses found in nasal lavage fluid were also found in middle ear fluid. Mixed bacterial and combined viral-bacterial infections were common. Only 15% of patients had no pathogen isolated from middle ear fluids. Using tissue culture techniques, we demonstrated that enterovirus and rhinovirus are also common middle ear pathogens. Our data reemphasize the significance of viruses as etiologic agents of acute otitis media and propose several questions regarding the viral-bacterial interactions and the types of viruses involved in the pathogenesis of the disease.

Original languageEnglish (US)
Pages (from-to)698-702
Number of pages5
JournalPediatrics
Volume77
Issue number5
StatePublished - 1986

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Otitis Media
Middle Ear
Nose
Nasal Lavage Fluid
Viruses
Rhinovirus
Enterovirus
Virus Diseases
Orthomyxoviridae
Tissue Culture Techniques
Paramyxoviridae Infections
Respiratory Syncytial Viruses
Bacterial Infections
Adenoviridae

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Presence of respiratory viruses in middle ear fluids and nasal wash specimens from children with acute otitis media. / Chonmaitree, T.; Howie, V. M.; Truant, A. L.

In: Pediatrics, Vol. 77, No. 5, 1986, p. 698-702.

Research output: Contribution to journalArticle

Chonmaitree, T. ; Howie, V. M. ; Truant, A. L. / Presence of respiratory viruses in middle ear fluids and nasal wash specimens from children with acute otitis media. In: Pediatrics. 1986 ; Vol. 77, No. 5. pp. 698-702.
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