Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis

Keyphrases

• Adult Neurogenesis 100%
• Affected Area 20%
• Alzheimer's Disease 20%
• Amyloid Plaques 20%
• Area CA1 20%
• Associative Learning 100%
• Conditioning Paradigms 20%
• Contextual Fear Conditioning 20%
• Dentate Gyrus 40%
• Disease Phenotype 20%
• Disease-causing mutations 100%
• Early Onset 20%
• Familial Alzheimer's Disease 100%
• Hippocampus 20%
• Knock-in Mouse Model 20%
• Learning Disorders 20%
• Long-term Plasticity 20%
• Memory Deficits 20%
• Memory Disorders 20%
• Plaque Deposition 20%
• Presenilin 100%
• Presenilin 1 mutation 20%
• Synapse 20%

Neuroscience

• Alzheimer's Disease 20%
• Amyloid Protein 20%
• Dentate Gyrus 40%
• Familial Alzheimer's Disease 100%
• Fear Conditioning 20%
• Hippocampus 20%
• Memory Disorder 20%
• Neurogenesis 100%
• Plaque 40%
• Presenilin 1 100%
• Synapse 20%
• Synaptic Plasticity 20%