Pressor response to beta-blocking drugs

M. G. Ziegler; L. C. Woodson

Pressor response to beta-blocking drugs

M. G. Ziegler, L. C. Woodson

Research output: Contribution to journal › Article

Abstract

A patient with essential hypertension had a prolonged period of uncontrollable high blood pressure during therapy with the nonspecific beta-blocker nadolol. A subsequent challenge with the beta₁-blocker atenolol caused a pressor response associated with diminished catecholamine release, impaired catecholamine clearance, loss of baroreflex response, and bradycardia. Beta-blocking drugs can lead to hypertension by causing fluid retention, reversal of catecholamine vasodilatation, or a direct pressor effect.

Original language	English (US)
Pages (from-to)	81-88
Number of pages	8
Journal	Clinical Therapeutics
Volume	7
Issue number	1
State	Published - Dec 1 1984

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

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Ziegler, M. G., & Woodson, L. C. (1984). Pressor response to beta-blocking drugs. Clinical Therapeutics, 7(1), 81-88.

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