Preterm premature rupture of membranes: Clinical outcomes of late-preterm infants

Julio Mateus, Karin Fox, Sangeeta Jain, Sunil Jain, Richard Latta, Jerry Cohen

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Objective: To determine gestational age-specific neonatal outcomes of late preterm infants delivered as a consequence of premature rupture of membranes (PROM). Methods: Retrospective cohort study of infants born to women delivered electively due to preterm PROM between 340/7 and 366/7 weeks of gestation. Neonatal outcomes were compared between those delivered at 340/7 to 346/7 weeks, at 350/7 to 35 6/7 weeks, and at 360/7 to 366/7 weeks. Results: 192 infants were identified. The 340/7 to 346/7 week infants had significantly higher neonatal intensive care admission rate (72.5%) compared to those at 350/7 to 356/7 weeks (22.8%) and at 36 to 366/7 weeks (17.8%) (P <.05). Neonatal respiratory distress syndrome was significantly higher at 340/7 to 34 6/7 weeks (35.4%) compared with 350/7 to 356/7 week and 360/7 to 366/7 week infants (10.5% and 4.1%; P <.05). The longest hospitalization occurred in the 340/7 to 346/7 week infants (248.5 ± 20.0 hours). Conclusion: Substantial short-term morbidity occurred in late preterm infants. The greatest number of complications affected infants born at 340/7 to 34 6/7 weeks.

Original languageEnglish (US)
Pages (from-to)60-65
Number of pages6
JournalClinical pediatrics
Issue number1
StatePublished - Jan 2010


  • Late-preterm infants
  • Neonatal morbidity
  • Preterm premature rupture of membranes
  • Respiratory distress syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'Preterm premature rupture of membranes: Clinical outcomes of late-preterm infants'. Together they form a unique fingerprint.

Cite this