Prevalence of antibodies to spotted fever group rickettsiae in humans and domestic animals in a Brazilian spotted fever-endemic area in the state of São Paulo, Brazil: Serologic evidence for infection by Rickettsia rickettsii and another spotted fever group rickettsia

Maurício C. Horta, Marcelo B. Labruna, Luis A. Sangioni, Manoella C B Vianna, Solange M. Gennari, Márcio A M Galvão, Claudio L. Mafra, Odilon Vidotto, Teresinha T S Schumaker, David Walker

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Abstract

In serum samples obtained from all the healthy humans, horses, dogs, and donkeys present on three farms in the Pedreira Municipality, an endemic area for Brazilian spotted fever, an indirect immunofluorescence assay (IFA) detected antibodies against Rickettsia rickettsii in 17 (77.3%) horses, 5 (31.3%) dogs (titers ranging from 64 to 4,048), and none of 4 donkeys or 50 humans. Five canine and eight equine sera with high antibody titers to R. rickettsii were also tested by IFA against R. bellii, R. akari, and R. africae antigens. Sera from two horses and two dogs that showed similar high antibody titers against two rickettsial antigens were evaluated after cross-absorption. Sera from seven horses and two dogs contained antibodies specific for R. rickettsii, and one dog serum had antibodies against a Rickettsia species very closely related to R. africae. The latter may have been caused by infection with the recently identified COOPERI strain.

Original languageEnglish (US)
Pages (from-to)93-97
Number of pages5
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume71
Issue number1
StatePublished - Jul 2004

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Rickettsia rickettsii
Rickettsia
Domestic Animals
Horses
Brazil
Fever
Dogs
Antibodies
Infection
Serum
Equidae
Antigens
Indirect Fluorescent Antibody Technique
Fluorescent Antibody Technique
Canidae

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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Prevalence of antibodies to spotted fever group rickettsiae in humans and domestic animals in a Brazilian spotted fever-endemic area in the state of São Paulo, Brazil : Serologic evidence for infection by Rickettsia rickettsii and another spotted fever group rickettsia. / Horta, Maurício C.; Labruna, Marcelo B.; Sangioni, Luis A.; Vianna, Manoella C B; Gennari, Solange M.; Galvão, Márcio A M; Mafra, Claudio L.; Vidotto, Odilon; Schumaker, Teresinha T S; Walker, David.

In: American Journal of Tropical Medicine and Hygiene, Vol. 71, No. 1, 07.2004, p. 93-97.

Research output: Contribution to journalArticle

Horta, Maurício C. ; Labruna, Marcelo B. ; Sangioni, Luis A. ; Vianna, Manoella C B ; Gennari, Solange M. ; Galvão, Márcio A M ; Mafra, Claudio L. ; Vidotto, Odilon ; Schumaker, Teresinha T S ; Walker, David. / Prevalence of antibodies to spotted fever group rickettsiae in humans and domestic animals in a Brazilian spotted fever-endemic area in the state of São Paulo, Brazil : Serologic evidence for infection by Rickettsia rickettsii and another spotted fever group rickettsia. In: American Journal of Tropical Medicine and Hygiene. 2004 ; Vol. 71, No. 1. pp. 93-97.
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