Prevalence of IgG antibodies to Ebola virus in individuals during an Ebola outbreak, Democratic Republic of the Congo, 1995

Kristina M. Busico, Katherine L. Marshall, Thomas Ksiazek, Thierry H. Roels, Yon Fleerackers, Heinz Feldmann, Ali S. Khan, C. J. Peters

Research output: Contribution to journalArticle

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Abstract

During the 1995 outbreak of Ebola (EBO) hemorrhagic fever in Kikwit, Democratic Republic of Congo, two surveys using a new ELISA for EBO (subtype Zaire) virus antigen were conducted to assess the prevalence of EBO IgG antibodies among residents of Kikwit and the surrounding area. The first study determined the proportion of antibody-positive individuals who were self-identified forest and city workers from the Kikwit area. Serum samples from 9 (2.2%) of 414 workers had IgG EBO antibodies. The second study determined the proportion of EBO antibody-positive individuals who lived in villages surrounding Kikwit. The prevalence of IgG EBO antibodies in this population was 9.3% (15/161). The difference in the overall prevalence of EBO antibodies may indicate that villagers have a greater chance of exposure to EBO virus compared with those living in and in close proximity to cities.

Original languageEnglish (US)
JournalJournal of Infectious Diseases
Volume179
Issue numberSUPPL. 1
StatePublished - 1999
Externally publishedYes

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Ebolavirus
Democratic Republic of the Congo
Disease Outbreaks
Immunoglobulin G
Antibodies
Ebola Hemorrhagic Fever
Enzyme-Linked Immunosorbent Assay
Antigens
Serum
Population

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Immunology

Cite this

Busico, K. M., Marshall, K. L., Ksiazek, T., Roels, T. H., Fleerackers, Y., Feldmann, H., ... Peters, C. J. (1999). Prevalence of IgG antibodies to Ebola virus in individuals during an Ebola outbreak, Democratic Republic of the Congo, 1995. Journal of Infectious Diseases, 179(SUPPL. 1).

Prevalence of IgG antibodies to Ebola virus in individuals during an Ebola outbreak, Democratic Republic of the Congo, 1995. / Busico, Kristina M.; Marshall, Katherine L.; Ksiazek, Thomas; Roels, Thierry H.; Fleerackers, Yon; Feldmann, Heinz; Khan, Ali S.; Peters, C. J.

In: Journal of Infectious Diseases, Vol. 179, No. SUPPL. 1, 1999.

Research output: Contribution to journalArticle

Busico, KM, Marshall, KL, Ksiazek, T, Roels, TH, Fleerackers, Y, Feldmann, H, Khan, AS & Peters, CJ 1999, 'Prevalence of IgG antibodies to Ebola virus in individuals during an Ebola outbreak, Democratic Republic of the Congo, 1995', Journal of Infectious Diseases, vol. 179, no. SUPPL. 1.
Busico, Kristina M. ; Marshall, Katherine L. ; Ksiazek, Thomas ; Roels, Thierry H. ; Fleerackers, Yon ; Feldmann, Heinz ; Khan, Ali S. ; Peters, C. J. / Prevalence of IgG antibodies to Ebola virus in individuals during an Ebola outbreak, Democratic Republic of the Congo, 1995. In: Journal of Infectious Diseases. 1999 ; Vol. 179, No. SUPPL. 1.
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