Prevalence of oral human papillomavirus by vaccination status among young adults (18–30 years old)

Jacqueline M. Hirth, Mihyun Chang, Vicente A. Resto, Fangjian Guo, Abbey B. Berenson

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


Background Although there is evidence that human papillomavirus (HPV) vaccination may protect against oral HPV infection, no current research has demonstrated this in the general population. Methods We used repeated cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) between 2009 and 2014. Participants 18–30 years who indicated whether they had received the HPV vaccine and provided an adequate oral sample were included (N = 3040). Oral HPV types were grouped by vaccine-type (types 6, 11, 16, 18) and by risk (high or low risk). Chi-square analyses compared oral HPV prevalence by vaccination status. Results Vaccinated adults had a lower prevalence of vaccine-type oral HPV (types 6, 11, 16, 18) compared to unvaccinated adults. Prevalence of non-vaccine high-risk oral HPV was similar between HPV vaccinated and unvaccinated participants. Conclusions HPV vaccination appears to provide protection against vaccine-type oral HPV infection among males and females in the general population.

Original languageEnglish (US)
Pages (from-to)3446-3451
Number of pages6
Issue number27
StatePublished - Jun 14 2017


  • HPV vaccination
  • Oral HPV infection
  • Oral cancer
  • Primary oral cancer prevention

ASJC Scopus subject areas

  • Molecular Medicine
  • General Immunology and Microbiology
  • General Veterinary
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


Dive into the research topics of 'Prevalence of oral human papillomavirus by vaccination status among young adults (18–30 years old)'. Together they form a unique fingerprint.

Cite this