Primary hepatic neuroendocrine carcinoma: Case reports and review of the literature

Primary neuroendocrine tumors of the liver are exceedingly rare, and unlike metastatic neuroendocrine tumors, rarely cause carcinoid syndrome. There are fewer than 150 cases reported in the current literature. We report two cases of primary hepatic neuroendocrine carcinomas of the liver. Both patients remain healthy without any recurrence to date. A review of the current literature regarding diagnosis, pathology, and management of this disease is included.