Primary malignant lymphomas of the breast

Nobby Mambo, J. S. Burke, J. J. Butler

Research output: Contribution to journalArticle

111 Citations (Scopus)

Abstract

14 cases of primary malignant lymphomas of the breast were found in the pathology files of the Institute mentioned, from 1944 to 1975. The lymphomas represented only 0.12% of 11,277 primary malignant breast tumors seen during the same period. There were no definite clinical features to distinguish the patients with lymphoma from those with breast carcinoma. All of the lymphomas had a diffuse pattern. 8 cases were classified as undifferentiated lymphoma, 5 as histiocytic, and 1 as the poorly differentiated lymphocytic, convoluted cell type. 4 patients had mastectomies and the remainder biopsies as their sole surgical procedure. 8 patients received post-surgical radiotherapy and all eventually had chemotherapy. The 5-yr survival rate for the 13 patients with follow-up was 49%. Patients with histiocytic lymphoma appeared to have a more favourable prognosis than those with the undifferentiated type. 6 of the latter patients are dead with a median survival of 7 mth, comparable to the reported survival of patients with American Burkitt's lymphoma. The patient with the convoluted cell type has developed acute blastic leukemia and is currently under therapy.

Original languageEnglish (US)
Pages (from-to)2033-2046
Number of pages14
JournalCancer
Volume39
Issue number5
StatePublished - 1977
Externally publishedYes

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Lymphoma
Breast
Breast Neoplasms
Burkitt Lymphoma
Survival
Lymphoma, Large B-Cell, Diffuse
Mastectomy
Non-Hodgkin's Lymphoma
Leukemia
Radiotherapy
Survival Rate
Pathology
Biopsy
Drug Therapy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Mambo, N., Burke, J. S., & Butler, J. J. (1977). Primary malignant lymphomas of the breast. Cancer, 39(5), 2033-2046.

Primary malignant lymphomas of the breast. / Mambo, Nobby; Burke, J. S.; Butler, J. J.

In: Cancer, Vol. 39, No. 5, 1977, p. 2033-2046.

Research output: Contribution to journalArticle

Mambo, N, Burke, JS & Butler, JJ 1977, 'Primary malignant lymphomas of the breast', Cancer, vol. 39, no. 5, pp. 2033-2046.
Mambo N, Burke JS, Butler JJ. Primary malignant lymphomas of the breast. Cancer. 1977;39(5):2033-2046.
Mambo, Nobby ; Burke, J. S. ; Butler, J. J. / Primary malignant lymphomas of the breast. In: Cancer. 1977 ; Vol. 39, No. 5. pp. 2033-2046.
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