Primary T-cell lymphoblastic lymphoma of the cavernous sinus: Case report

Sarfaraz Sadruddin, L. Jeffrey Medeiros, Franco DeMonte

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

The rare occurrence of T-cell lymphoblastic lymphoma as a primary tumor in the cavernous sinus is described. The patient, a 17-year-old girl, presented with right-sided ophthalmic and maxillary neuropathy and diplopia due to neuropathies of cranial nerves III and VI. An enhancing mass in the cavernous sinus was identified on MR imaging. Dexamethasone was prescribed but did not provide symptomatic relief. Rapid progression of symptoms led to open biopsy, and a diagnosis of T-cell lymphoblastic lymphoma was made. The patient promptly underwent aggressive chemotherapy in which a modified hyper-cyclophosphamide, vincristine, and dexamethasone without doxorubicin regimen with concurrent radiotherapy was used. The patient achieved complete remission and is currently completing the 2-year maintenance phase of chemotherapy.

Original languageEnglish (US)
Pages (from-to)94-97
Number of pages4
JournalJournal of Neurosurgery: Pediatrics
Volume5
Issue number1
DOIs
StatePublished - Jan 1 2010
Externally publishedYes

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Keywords

  • Cavernous sinus
  • Cavernous sinus syndrome
  • Hyper-CVAD
  • Primary central nervous system lymphoma
  • T-cell lymphoblastic lymphoma

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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