Prognosis and treatment of advanced squamous cell carcinoma secondary to epidermodysplasia verruciformis

A worldwide analysis of 11 patients

T. A. Kaspar, Richard Wagner, S. Jablonska, M. Niimura, S. K. Tyring

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Data were collected from three medical centers in the USA, Poland, and Japan regarding 11 patients with advanced squamous cell carcinoma (SCC) secondary to epidermodysplasia verruciformis (EV). Analysis was conducted regarding primary tumor location, age at onset of EV, age at diagnosis of SCC, treatment of SCC, history of local tumor recurrence, presence of metastases, and age at death. Three of 11 patients developed both lymph node and visceral metastases and the mean patient age at death was 44 years (N = 6) with no patient to date living past 54 years. Mean patient survival time following metastases was 1.7 years (N = 2). Human papilloma virus typing of nine patients was performed. Current controversies regarding the treatment of patients with advanced SCC in the setting of EV are reviewed.

Original languageEnglish (US)
Pages (from-to)237-240
Number of pages4
JournalJournal of Dermatologic Surgery and Oncology
Volume17
Issue number3
StatePublished - 1991

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Epidermodysplasia Verruciformis
Squamous Cell Carcinoma
Neoplasm Metastasis
Papillomaviridae
Therapeutics
Poland
Age of Onset
Neoplasms
Japan
Survival Rate
Lymph Nodes
Recurrence

ASJC Scopus subject areas

  • Dermatology
  • Oncology

Cite this

Prognosis and treatment of advanced squamous cell carcinoma secondary to epidermodysplasia verruciformis : A worldwide analysis of 11 patients. / Kaspar, T. A.; Wagner, Richard; Jablonska, S.; Niimura, M.; Tyring, S. K.

In: Journal of Dermatologic Surgery and Oncology, Vol. 17, No. 3, 1991, p. 237-240.

Research output: Contribution to journalArticle

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