@article{5eda79e9a0fb4422a3d7f147d9092ce1,
title = "Prolonged and extended impacts of SARS-CoV-2 on the olfactory neurocircuit",
abstract = "The impact of SARS-CoV-2 on the olfactory pathway was studied over several time points using Syrian golden hamsters. We found an incomplete recovery of the olfactory sensory neurons, prolonged activation of glial cells in the olfactory bulb, and a decrease in the density of dendritic spines within the hippocampus. These data may be useful for elucidating the mechanism underlying long-lasting olfactory dysfunction and cognitive impairment as a post-acute COVID-19 syndrome.",
author = "Megumi Kishimoto-Urata and Shinji Urata and Ryoji Kagoya and Fumiaki Imamura and Shin Nagayama and Reyna, {Rachel A.} and Junki Maruyama and Tatsuya Yamasoba and Kenji Kondo and Sanae Hasegawa-Ishii and Slobodan Paessler",
note = "Funding Information: We would like to thank both the histology core for the HE-staining and imaging core for use of the microscope at UTMB, C.A. Grant, M.A. Micci, K. Suenaga, and H. Iigusa for technical support in preparation of the manuscript, as well as R. Kamei T.Higashi and Y. Kashiwagi for discussions. We also thank T. Makishima for critical reading of the manuscript. This project was funded by John S. Dunn Endowment to S.P. Funding Information: We would like to thank both the histology core for the HE-staining and imaging core for use of the microscope at UTMB, C.A. Grant, M.A. Micci, K. Suenaga, and H. Iigusa for technical support in preparation of the manuscript, as well as R. Kamei T.Higashi and Y. Kashiwagi for discussions. We also thank T. Makishima for critical reading of the manuscript. This project was funded by John S. Dunn Endowment to S.P. Publisher Copyright: {\textcopyright} 2022, The Author(s).",
year = "2022",
month = dec,
doi = "10.1038/s41598-022-09731-7",
language = "English (US)",
volume = "12",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",
number = "1",
}