Propagation of human candidate calicivirus in cell culture

W. D. Cubitt, A. D.T. Barrett

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Evidence is presented for the first time that a human candidate calicivirus (HCV) replicates in human embryo kidney cells when trypsin is incorporated in the culture medium. The virus multiplies in the presence of actinomycin D and radiolabelling experiments with [3H]uridine indicate that it has an RNA genome. These observations provide further support for the view that HCV should be tentatively classified as a member of the Caliciviridae.

Original languageEnglish (US)
Pages (from-to)1123-1126
Number of pages4
JournalJournal of General Virology
Volume65
Issue number6
DOIs
StatePublished - Jan 1 1984
Externally publishedYes

ASJC Scopus subject areas

  • Virology

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