Protease inhibitors do not affect antibody responses to pneumococcal vaccination

Indhira De La Rosa; Iona M. Munjal; Maria Rodriguez-Barradas; Xiaoying Yu; Liise Anne Pirofski; Daniel Mendoza

doi:10.1128/CVI.00026-16

Protease inhibitors do not affect antibody responses to pneumococcal vaccination

Indhira De La Rosa
, Iona M. Munjal
, Maria Rodriguez-Barradas
, Xiaoying Yu
, Liise Anne Pirofski
, Daniel Mendoza

Research output: Contribution to journal › Article › peer-review

Abstract

HIV⁺ subjects on optimal antiretroviral therapy have persistently impaired antibody responses to pneumococcal vaccination. We explored the possibility that this effect may be due to HIV protease inhibitors (PIs). We found that in humans and mice, PIs do not affect antibody production in response to pneumococcal vaccination.

Original language	English (US)
Pages (from-to)	524-529
Number of pages	6
Journal	Clinical and Vaccine Immunology
Volume	23
Issue number	6
DOIs	https://doi.org/10.1128/CVI.00026-16
State	Published - Jun 2016
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Clinical Biochemistry
Microbiology (medical)

Access to Document

10.1128/CVI.00026-16

Cite this

@article{2abcfb37352d440786bdd8b26800e814,

title = "Protease inhibitors do not affect antibody responses to pneumococcal vaccination",

abstract = "HIV+ subjects on optimal antiretroviral therapy have persistently impaired antibody responses to pneumococcal vaccination. We explored the possibility that this effect may be due to HIV protease inhibitors (PIs). We found that in humans and mice, PIs do not affect antibody production in response to pneumococcal vaccination.",

author = "\{De La Rosa\}, Indhira and Munjal, \{Iona M.\} and Maria Rodriguez-Barradas and Xiaoying Yu and Pirofski, \{Liise Anne\} and Daniel Mendoza",

year = "2016",

month = jun,

doi = "10.1128/CVI.00026-16",

language = "English (US)",

volume = "23",

pages = "524--529",

journal = "Clinical and Vaccine Immunology",

issn = "1556-6811",

publisher = "American Society for Microbiology",

number = "6",

}

TY - JOUR

T1 - Protease inhibitors do not affect antibody responses to pneumococcal vaccination

AU - De La Rosa, Indhira

AU - Munjal, Iona M.

AU - Rodriguez-Barradas, Maria

AU - Yu, Xiaoying

AU - Pirofski, Liise Anne

AU - Mendoza, Daniel

PY - 2016/6

Y1 - 2016/6

N2 - HIV+ subjects on optimal antiretroviral therapy have persistently impaired antibody responses to pneumococcal vaccination. We explored the possibility that this effect may be due to HIV protease inhibitors (PIs). We found that in humans and mice, PIs do not affect antibody production in response to pneumococcal vaccination.

AB - HIV+ subjects on optimal antiretroviral therapy have persistently impaired antibody responses to pneumococcal vaccination. We explored the possibility that this effect may be due to HIV protease inhibitors (PIs). We found that in humans and mice, PIs do not affect antibody production in response to pneumococcal vaccination.

UR - https://www.scopus.com/pages/publications/84973473369

UR - https://www.scopus.com/pages/publications/84973473369#tab=citedBy

U2 - 10.1128/CVI.00026-16

DO - 10.1128/CVI.00026-16

M3 - Article

C2 - 27074938

AN - SCOPUS:84973473369

SN - 1556-6811

VL - 23

SP - 524

EP - 529

JO - Clinical and Vaccine Immunology

JF - Clinical and Vaccine Immunology

IS - 6

ER -

Protease inhibitors do not affect antibody responses to pneumococcal vaccination

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this