Protection by inhibition of poly (ADP-ribose) synthetase against oxidant injury in cardiac myoblasts in vitro

Keyphrases

• Oxidative Damage 100%
• Poly(ADP-ribose) Synthetase 100%
• Cardiac Myoblasts 100%
• Peroxynitrite 50%
• Hydrogen Peroxide 33%
• Mitochondrial Respiration 33%
• NO Donors 33%
• Pharmacological Inhibitors 16%
• Deoxygenation 16%
• Knock-in Mouse Model 8%
• Macrophages 8%
• Dose Effect 8%
• Smooth muscle Cells 8%
• Hydroxyl Radical 8%
• Cytotoxicity 8%
• Reactive Oxidant Species 8%
• Cell-derived 8%
• High Concentration 8%
• Hypoxia 8%
• Fibroblast Cell Line 8%
• D-penicillamine 8%
• Myocardial Ischemia-reperfusion Injury 8%
• Single Strand 8%
• 3-aminobenzamide 8%
• Strand Breaks 8%
• H9c2 Cardiac Cells 8%
• Formazan 8%
• Nicotinamide 8%
• Nitroso 8%
• NONOate 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Injury 100%
• Synthetase 100%
• Oxidizing Agent 100%
• Poly(adenosine Diphosphate Ribose) 100%
• Peroxynitrite 54%
• Hydrogen Peroxide 36%
• Knockout Mouse 9%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase Inhibitor 9%
• Hydroxyl Radical 9%
• Single Stranded DNA 9%
• Hypoxia 9%
• Penicillamine 9%
• Myocardial Ischemia Reperfusion Injury 9%
• 3 Aminobenzamide 9%
• Formazan 9%
• Nicotinamide 9%
• Cytotoxicity 9%