Protein characterization of Australian spotted fever group rickettsiae and monoclonal antibody typing of Rickettsia honei

J. Stenos, B. Ross, H. M. Feng, P. Crocquet-Valdes, D. Walker

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Abstract

Rickettsial proteins rOmp A and rOmp B exist in both Rickettsia australis and Rickettsia honei but differ in molecular weight and antigenicity; in addition, they produce distinct immunogenic responses and appear to be to conformationally dependent antigens. Species-specific monoclonal antibodies for other spotted fever group rickettsial species did not react with R. honei. A PCR product of the repeat region of the rOmp A gene from R. honei was amplified and calculated to contain 11 repeat units.

Original languageEnglish (US)
Pages (from-to)261-263
Number of pages3
JournalJournal of Clinical Microbiology
Volume35
Issue number1
StatePublished - Jan 1 1997

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ASJC Scopus subject areas

  • Microbiology (medical)

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