Protein characterization of Australian spotted fever group rickettsiae and monoclonal antibody typing of Rickettsia honei

J. Stenos; B. Ross; H. M. Feng; P. Crocquet-Valdes; D. Walker

doi:10.1128/jcm.35.1.261-263.1997

Protein characterization of Australian spotted fever group rickettsiae and monoclonal antibody typing of Rickettsia honei

J. Stenos, B. Ross, H. M. Feng, P. Crocquet-Valdes, D. Walker

Pathology

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Rickettsial proteins rOmp A and rOmp B exist in both Rickettsia australis and Rickettsia honei but differ in molecular weight and antigenicity; in addition, they produce distinct immunogenic responses and appear to be to conformationally dependent antigens. Species-specific monoclonal antibodies for other spotted fever group rickettsial species did not react with R. honei. A PCR product of the repeat region of the rOmp A gene from R. honei was amplified and calculated to contain 11 repeat units.

Original language	English (US)
Pages (from-to)	261-263
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	35
Issue number	1
DOIs	https://doi.org/10.1128/jcm.35.1.261-263.1997
State	Published - 1997

ASJC Scopus subject areas

Microbiology (medical)

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10.1128/jcm.35.1.261-263.1997

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abstract = "Rickettsial proteins rOmp A and rOmp B exist in both Rickettsia australis and Rickettsia honei but differ in molecular weight and antigenicity; in addition, they produce distinct immunogenic responses and appear to be to conformationally dependent antigens. Species-specific monoclonal antibodies for other spotted fever group rickettsial species did not react with R. honei. A PCR product of the repeat region of the rOmp A gene from R. honei was amplified and calculated to contain 11 repeat units.",

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year = "1997",

doi = "10.1128/jcm.35.1.261-263.1997",

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AU - Crocquet-Valdes, P.

AU - Walker, D.

PY - 1997

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AB - Rickettsial proteins rOmp A and rOmp B exist in both Rickettsia australis and Rickettsia honei but differ in molecular weight and antigenicity; in addition, they produce distinct immunogenic responses and appear to be to conformationally dependent antigens. Species-specific monoclonal antibodies for other spotted fever group rickettsial species did not react with R. honei. A PCR product of the repeat region of the rOmp A gene from R. honei was amplified and calculated to contain 11 repeat units.

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Protein characterization of Australian spotted fever group rickettsiae and monoclonal antibody typing of Rickettsia honei

Abstract

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