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Protein characterization of Australian spotted fever group rickettsiae and monoclonal antibody typing of Rickettsia honei

  • J. Stenos
  • , B. Ross
  • , H. M. Feng
  • , P. Crocquet-Valdes
  • , D. Walker

Research output: Contribution to journalArticlepeer-review

Abstract

Rickettsial proteins rOmp A and rOmp B exist in both Rickettsia australis and Rickettsia honei but differ in molecular weight and antigenicity; in addition, they produce distinct immunogenic responses and appear to be to conformationally dependent antigens. Species-specific monoclonal antibodies for other spotted fever group rickettsial species did not react with R. honei. A PCR product of the repeat region of the rOmp A gene from R. honei was amplified and calculated to contain 11 repeat units.

Original languageEnglish (US)
Pages (from-to)261-263
Number of pages3
JournalJournal of Clinical Microbiology
Volume35
Issue number1
DOIs
StatePublished - 1997

ASJC Scopus subject areas

  • Microbiology (medical)

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