Abstract
Models of protein hydration are becoming increasingly more accurate in comparison with experimental data. The recent success of these models implies that the major features of the solvation layers are dominated by local correlations and that such correlations are universal. The excellent agreement between theoretical and experimental solvent electron density radial distributions marks a significant success in our ability to accurately model macromolecular hydration.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 218-221 |
| Number of pages | 4 |
| Journal | Current Opinion in Structural Biology |
| Volume | 8 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 1998 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Molecular Biology
- Structural Biology
Cite this
Protein hydration density : Theory, simulations and crystallography. / Pettitt, Bernard; Makarov, Vladimir A.; Andrews, B. Kim.
In: Current Opinion in Structural Biology, Vol. 8, No. 2, 04.1998, p. 218-221.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Protein hydration density
T2 - Theory, simulations and crystallography
AU - Pettitt, Bernard
AU - Makarov, Vladimir A.
AU - Andrews, B. Kim
PY - 1998/4
Y1 - 1998/4
N2 - Models of protein hydration are becoming increasingly more accurate in comparison with experimental data. The recent success of these models implies that the major features of the solvation layers are dominated by local correlations and that such correlations are universal. The excellent agreement between theoretical and experimental solvent electron density radial distributions marks a significant success in our ability to accurately model macromolecular hydration.
AB - Models of protein hydration are becoming increasingly more accurate in comparison with experimental data. The recent success of these models implies that the major features of the solvation layers are dominated by local correlations and that such correlations are universal. The excellent agreement between theoretical and experimental solvent electron density radial distributions marks a significant success in our ability to accurately model macromolecular hydration.
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UR - http://www.scopus.com/inward/citedby.url?scp=0032054168&partnerID=8YFLogxK
U2 - 10.1016/S0959-440X(98)80042-0
DO - 10.1016/S0959-440X(98)80042-0
M3 - Article
VL - 8
SP - 218
EP - 221
JO - Current Opinion in Structural Biology
JF - Current Opinion in Structural Biology
SN - 0959-440X
IS - 2
ER -