Protein kinase G phosphorylates soluble guanylyl cyclase on serine 64 and inhibits its activity

Keyphrases

• Active Form 9%
• Alanine mutation 9%
• CGMP-dependent Protein Kinase 9%
• Constitutively Active 9%
• Cyclic GMP 18%
• Desensitization 9%
• Endothelial Nitric Oxide 9%
• Negative Feedback Loop 9%
• Nitric Oxide 45%
• Overexpression 9%
• Phospho-specific Antibodies 9%
• Phosphomimetic 9%
• Phosphorylation 27%
• Phosphorylation Sites 9%
• Protein Kinase G 100%
• Soluble Guanylyl Cyclase 100%
• VASP Phosphorylation 9%
• Vmax 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Alanine 9%
• Cyclic GMP Dependent Protein Kinase 100%
• Desensitization 9%
• Dimer 9%
• Guanylate Cyclase 100%
• Nitric Oxide 54%
• Phosphorus 32 9%
• Phosphospecific Antibody 9%
• Serine 100%
• Vasodilator Stimulated Phosphoprotein 9%

Biochemistry, Genetics and Molecular Biology

• Alanine 9%
• Antibodies 9%
• CGMP-dependent Protein Kinase 100%
• Guanylate Cyclase 100%
• Maximum Reaction Velocity 9%
• Nitric Oxide 54%
• Phosphomimetics 9%
• Serine 100%
• Wild Type 18%