Protein supplementation increases Postexercise plasma Myostatin concentration after 8 weeks of resistance training in young physically active subjects

Antonio Paoli, Quirico F. Pacelli, Marco Neri, Luana Toniolo, Pasqua Cancellara, Marta Canato, Tatiana Moro, Marco Quadrelli, Aldo Morra, Diego Faggian, Mario Plebani, Antonino Bianco, Carlo Reggiani

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Myostatin (MSTN) is a negative regulator of muscle growth even if some studies have shown a counterintuitive positive correlation between MSTN and muscle mass (MM). Our aim was to investigate the influence of 2 months of resistance training (RT) and diets with different protein contents on plasma MSTN, interleukin 1 beta (IL-1β), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-α), and insulin-like growth factor 1 (IGF-1). Eighteen healthy volunteers were randomly divided in two groups: high protein (HP) and normal protein (NP) groups. Different protein diet contents were 1.8 and 0.85g of protein kg bw-1 day-1 for HP and NP, respectively. Subjects underwent 8 weeks of standardized progressive RT. MSTN, IGF-1, IL-1β, IL-6, and TNF-α were analyzed before and after the first and the last training sessions. Lean body mass, MM, upper-limb muscle area, and strength were measured. Plasma MSTN showed a significant increase (P

Original languageEnglish (US)
Pages (from-to)137-143
Number of pages7
JournalJournal of Medicinal Food
Volume18
Issue number1
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Fingerprint

Myostatin
Resistance Training
Proteins
Somatomedins
Interleukin-1beta
Muscles
Interleukin-6
Diet
Muscle Strength
Upper Extremity
Healthy Volunteers
Tumor Necrosis Factor-alpha
Growth

Keywords

  • cytokines
  • diet
  • exercise
  • myostatin
  • nutritional supplement

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Medicine(all)

Cite this

Protein supplementation increases Postexercise plasma Myostatin concentration after 8 weeks of resistance training in young physically active subjects. / Paoli, Antonio; Pacelli, Quirico F.; Neri, Marco; Toniolo, Luana; Cancellara, Pasqua; Canato, Marta; Moro, Tatiana; Quadrelli, Marco; Morra, Aldo; Faggian, Diego; Plebani, Mario; Bianco, Antonino; Reggiani, Carlo.

In: Journal of Medicinal Food, Vol. 18, No. 1, 01.01.2015, p. 137-143.

Research output: Contribution to journalArticle

Paoli, A, Pacelli, QF, Neri, M, Toniolo, L, Cancellara, P, Canato, M, Moro, T, Quadrelli, M, Morra, A, Faggian, D, Plebani, M, Bianco, A & Reggiani, C 2015, 'Protein supplementation increases Postexercise plasma Myostatin concentration after 8 weeks of resistance training in young physically active subjects', Journal of Medicinal Food, vol. 18, no. 1, pp. 137-143. https://doi.org/10.1089/jmf.2014.0004
Paoli, Antonio ; Pacelli, Quirico F. ; Neri, Marco ; Toniolo, Luana ; Cancellara, Pasqua ; Canato, Marta ; Moro, Tatiana ; Quadrelli, Marco ; Morra, Aldo ; Faggian, Diego ; Plebani, Mario ; Bianco, Antonino ; Reggiani, Carlo. / Protein supplementation increases Postexercise plasma Myostatin concentration after 8 weeks of resistance training in young physically active subjects. In: Journal of Medicinal Food. 2015 ; Vol. 18, No. 1. pp. 137-143.
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