Proteomics Approach to Identify Biomarkers in Neurodegenerative Diseases

Annapurna Nayak, Gregory Salt, Sunil K. Verma, Uday Kishore

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

This chapter examines the use of proteomics in understanding pathogenesis and identifying possible biomarkers in a range of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and prion diseases. We have attempted to look at the neuroproteomic approach from a biomarker discovery point of view. Novel biomarkers can pave the way for new therapeutic targets and lead us to a better understanding of the pathogenesis involved in the neurodegenerative diseases.

Original languageEnglish (US)
Title of host publicationInternational Review of Neurobiology
EditorsMichael J. Hurley
PublisherAcademic Press Inc.
Pages59-86
Number of pages28
ISBN (Print)9780128014806
DOIs
StatePublished - 2015

Publication series

NameInternational Review of Neurobiology
Volume121
ISSN (Print)0074-7742
ISSN (Electronic)2162-5514

Keywords

  • Biomarker
  • Neurodegeneration
  • Neuroinflammation
  • Proteomic

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience

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  • Cite this

    Nayak, A., Salt, G., Verma, S. K., & Kishore, U. (2015). Proteomics Approach to Identify Biomarkers in Neurodegenerative Diseases. In M. J. Hurley (Ed.), International Review of Neurobiology (pp. 59-86). (International Review of Neurobiology; Vol. 121). Academic Press Inc.. https://doi.org/10.1016/bs.irn.2015.05.003