Keyphrases
Hepatitis C Virus Replication
100%
Fluoro
100%
Monophosphate
100%
Pronucleotides
100%
PSI-7851
100%
Pan-genome
100%
Replicon
50%
Genotype 1
40%
Hepatitis C Virus
30%
RNA-dependent RNA Polymerase (RdRP)
20%
Antiviral Activity
20%
Genotype 2a
20%
Nucleoside Analogues
20%
Genotype 1b
20%
NS5B
20%
Virus
10%
Infected Individual
10%
DNA Polymerase
10%
Mitochondrial Toxicity
10%
Recombinant
10%
Liver
10%
RNA Synthesis
10%
Infectious Virus
10%
Cytotoxicity
10%
Cellular DNA
10%
Hepatitis C Virus Infection
10%
High Concentration
10%
Triphosphate
10%
Cross-resistance
10%
HCV NS5B Polymerase
10%
Modified nucleosides
10%
Highly Active
10%
Effective Concentration
10%
Replicon-RNA
10%
5′-monophosphate
10%
Activity Profile
10%
Mean Standard Deviation
10%
Cellular RNA
10%
Replicon Cell
10%
Virus Replication Cycle
10%
Clear Cell
10%
Resistance Genotype
10%
S282T
10%
Inhibitory Concentration
10%
Hepatitis C Virus Inhibitors
10%
Bone Marrow Toxicity
10%
High Barrier
10%
Multiple Ascending Dose
10%
Nucleotide Inhibitors
10%
Cytotoxicity Profile
10%
Viral Rebound
10%
Barrier Resistance
10%
Biochemistry, Genetics and Molecular Biology
Hepatitis C Virus
100%
Virus Replication
100%
Replicon
100%
Genotyping
100%
NS5B
42%
Cytotoxicity
28%
RNA Polymerase
28%
Antiviral Activity
28%
Nucleoside Analog
28%
DNA Polymerase
14%
RNA Synthesis
14%
RNA
14%
Virus Infectivity
14%
Polymerase
14%
EC50
14%
IC50
14%
Virus Inhibition
14%
Rebound
14%
Immunology and Microbiology
Viral Replication
100%
Hepatitis C Virus
100%
Replicon
100%
NS5B
50%
RNA Polymerase
33%
Cytotoxicity
33%
Antiviral Activity
33%
DNA Polymerase
16%
Virus Infectivity
16%
RNA Synthesis
16%
Hepatitis C
16%
EC50
16%
Virus Inhibition
16%
IC50
16%
Rebound
16%
Replicon Cell
16%
Virus
16%
In Vitro
16%
Ribonucleic Acid
16%
Pharmacology, Toxicology and Pharmaceutical Science
Hepatitis C Virus
100%
Antiviral Activity
33%
RNA Polymerase
33%
Cytotoxicity
33%
Nucleoside Analog
33%
DNA Polymerase
16%
Mitochondrial Toxicity
16%
Hepatitis C
16%
Virus Infectivity
16%
Cell DNA
16%
IC50
16%
Bone Marrow Toxicity
16%
EC50
16%