PTHrP promotes colon cancer cell migration and invasion in an integrin α6β4-dependent manner through activation of Rac1

Keyphrases

• Cancer Cell Migration 100%
• Cancer Invasion 100%
• Cell Invasion 20%
• Cell Migration 20%
• Chemical Inhibitors 10%
• Colon Cancer 10%
• Colon Cancer Cells 100%
• Colon Tissue 10%
• Expression Activity 10%
• Growth Hormone Receptor 10%
• Guanine nucleotide Exchange Factor 10%
• Human Colon Cancer 10%
• Human Colon Cancer Cells 10%
• Integrin 100%
• Knockdown 10%
• LoVo 10%
• LoVo Cells 10%
• Mediating Effect 10%
• Overexpressing 10%
• Parathyroid Hormone-related Protein (PTHrP) 100%
• Phosphatidylinositol 3-kinase Pathway 10%
• Phosphoinositide 3-kinase (PI3K) 10%
• Protein Activity 10%
• Protein Expression 10%
• Protein Production 10%
• Rac GTPase 10%
• Rac1 100%
• Rac1 Activation 10%
• TIAM1 30%
• Tumor 10%

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• Cell Invasion 100%
• Cell Migration 100%
• Colon 100%
• Growth Factor Receptor 10%
• GTPase 10%
• Guanine Nucleotide Exchange Factor 10%
• Integrin 100%
• Parathyroid Hormone-Related Protein 100%
• Phosphoinositide 3-Kinase 20%
• Protein Expression 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Colon Carcinoma 100%
• Growth Factor Receptor 10%
• Guanine Nucleotide Exchange Factor 10%
• Guanosine Triphosphatase 10%
• Integrin 100%
• Parathyroid Hormone Related Protein 100%
• Phosphatidylinositol 3 Kinase 20%