Purines inhibit poly(ADP-ribose polymerase activation and modulate oxidant-induced cell death

Keyphrases

• Purine 100%
• Poly(ADP-ribose) Polymerase 100%
• Induced Cell Death 100%
• Hypoxanthine 80%
• PARP Inhibitor (PARPi) 40%
• Adenosine 30%
• Peroxynitrite 30%
• Inosine 30%
• Inhibitory Effect 20%
• Nicotinamide Adenine Dinucleotide (NAD+) 20%
• Necrotic Cell Death 20%
• Macrophages 10%
• Cell Surface 10%
• Histone 10%
• Shock 10%
• Cell Death 10%
• Inflammation Injury 10%
• Cell Injury 10%
• Thymocytes 10%
• Mitochondrial Respiration 10%
• Interferon-α (IFN-α) 10%
• Adenosine Receptors 10%
• Ischemia-reperfusion Injury 10%
• DNA Fragmentation 10%
• Endotoxin 10%
• Mitochondrial Alterations 10%
• Caspase Activity 10%
• Anti-inflammatory Effect 10%
• ADP-ribose 10%
• Superoxide Production 10%
• Activity Fragmentation 10%
• Overactivation 10%
• RAW Macrophages 10%
• Cytoprotective Agents 10%
• Mitochondrial Depolarization 10%
• LPS-stimulated Macrophages 10%
• Nitrite Production 10%
• Polymerized 10%
• Purine Compounds 10%
• Nicotinamide Ribose 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Purine Derivative 100%
• Oxidizing Agent 100%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 100%
• Hypoxanthine 80%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase Inhibitor 40%
• Adenosine 30%
• Peroxynitrite 30%
• Inosine 30%
• Cytoprotective Agent 20%
• Inflammation 10%
• Histone 10%
• Superoxide 10%
• Caspase 10%
• Adenosine Triphosphate 10%
• Reperfusion Injury 10%
• Endotoxin 10%
• Purine 10%
• Interferon 10%
• Adenosine Receptor 10%
• Nitrite 10%
• Adenosine Diphosphate Ribose 10%
• Nicotinamide 10%