Pyrosequencing of the genital microbiotas of HIV-seropositive and -seronegative women reveals lactobacillus iners as the predominant lactobacillus species

Gregory T. Spear, Douglas Gilbert, Alan L. Landay, Reza Zariffard, Audrey L. French, Pranjal Patel, Patrick M. Gillevet

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

The species of vaginal lactobacilli in HIV-seropositive and -seronegative women were determined by 16S gene pyrosequencing. Lactobacillus iners sequences were the predominant lactobacillus sequences in 66% of HIV+women and 90% of HIV- women. This has implications for resistance of HIV + and HIV- women to genital colonization by pathogenic organisms.

Original languageEnglish (US)
Pages (from-to)378-381
Number of pages4
JournalApplied and Environmental Microbiology
Volume77
Issue number1
DOIs
StatePublished - Jan 2011
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

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