Q wave and non-Q wave myocardial infarction: a multivariate analysis of survival experience and clinical outcome after first diagnosis at a tertiary care hospital.

R. M. Karim, H. A. Khawaja, S. Naz, S. S. Merchant, I. A. Momin, I. Lalani, Asif A. Sewani, S. Akhtar, A. Ahmed

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

INTRODUCTION: Myocardial infarction (MI) is a well-recognized clinical entity with a worldwide distribution. In the United States alone, 1.5 million cases of MI occur per year. This study compares the in-hospital mortality, 1 year mortality and time to death following a first Q-wave or non Q-wave myocardial infarction (MI). METHODS: One thousand five hundred and ninety-six patients were admitted at the Aga Khan University Hospital with a diagnosis of MI over a period of four years of whom 420 patients met our inclusion criteria. Data was collected from the patients' medical records and on telephone using a pretested questionnaire. Logistic regression and Cox proportional hazard models were used to analyze the data. RESULTS: The mean age +/- sd of the patients was 59 +/- 10 years. Of the total patients, 151(36%) and 269(64%) suffered non-Q wave and Q-wave MI respectively. A higher in hospital mortality was observed in patients with Q-wave MI (n = 64, 23.8%) than those with non-Q wave MI [n = 16 (10.6%); adjusted OR = 2.76, 95% CI: 1.5-5.01]. Similarly, patients having Q-wave MI experienced increased 1 year mortality (n = 77, 28.6%) compared to patients suffering non-Q wave MI [n = 26 (17.2%); adjusted OR = 2.04, 95% CI: 1.21-3.43]. CONCLUSION: Patients with Q-wave MI had a worse prognosis compared with patients with non-Q-wave MI and therefore warrant a closer follow up. Further prospective studies are needed to evaluate the efficacy of early aggressive interventions in modifying the natural history of this disease.

Original languageEnglish (US)
Pages (from-to)149-154
Number of pages6
JournalJournal of the Pakistan Medical Association
Volume49
Issue number6
StatePublished - Jun 1 1999
Externally publishedYes

Fingerprint

Tertiary Healthcare
Tertiary Care Centers
Multivariate Analysis
Myocardial Infarction
Survival
Hospital Mortality
Mortality
Proportional Hazards Models
Telephone
Medical Records
Logistic Models
Prospective Studies

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Q wave and non-Q wave myocardial infarction : a multivariate analysis of survival experience and clinical outcome after first diagnosis at a tertiary care hospital. / Karim, R. M.; Khawaja, H. A.; Naz, S.; Merchant, S. S.; Momin, I. A.; Lalani, I.; Sewani, Asif A.; Akhtar, S.; Ahmed, A.

In: Journal of the Pakistan Medical Association, Vol. 49, No. 6, 01.06.1999, p. 149-154.

Research output: Contribution to journalArticle

Karim, R. M. ; Khawaja, H. A. ; Naz, S. ; Merchant, S. S. ; Momin, I. A. ; Lalani, I. ; Sewani, Asif A. ; Akhtar, S. ; Ahmed, A. / Q wave and non-Q wave myocardial infarction : a multivariate analysis of survival experience and clinical outcome after first diagnosis at a tertiary care hospital. In: Journal of the Pakistan Medical Association. 1999 ; Vol. 49, No. 6. pp. 149-154.
@article{0521e14a164844f9ae2fe6d76d2a0fd8,
title = "Q wave and non-Q wave myocardial infarction: a multivariate analysis of survival experience and clinical outcome after first diagnosis at a tertiary care hospital.",
abstract = "INTRODUCTION: Myocardial infarction (MI) is a well-recognized clinical entity with a worldwide distribution. In the United States alone, 1.5 million cases of MI occur per year. This study compares the in-hospital mortality, 1 year mortality and time to death following a first Q-wave or non Q-wave myocardial infarction (MI). METHODS: One thousand five hundred and ninety-six patients were admitted at the Aga Khan University Hospital with a diagnosis of MI over a period of four years of whom 420 patients met our inclusion criteria. Data was collected from the patients' medical records and on telephone using a pretested questionnaire. Logistic regression and Cox proportional hazard models were used to analyze the data. RESULTS: The mean age +/- sd of the patients was 59 +/- 10 years. Of the total patients, 151(36{\%}) and 269(64{\%}) suffered non-Q wave and Q-wave MI respectively. A higher in hospital mortality was observed in patients with Q-wave MI (n = 64, 23.8{\%}) than those with non-Q wave MI [n = 16 (10.6{\%}); adjusted OR = 2.76, 95{\%} CI: 1.5-5.01]. Similarly, patients having Q-wave MI experienced increased 1 year mortality (n = 77, 28.6{\%}) compared to patients suffering non-Q wave MI [n = 26 (17.2{\%}); adjusted OR = 2.04, 95{\%} CI: 1.21-3.43]. CONCLUSION: Patients with Q-wave MI had a worse prognosis compared with patients with non-Q-wave MI and therefore warrant a closer follow up. Further prospective studies are needed to evaluate the efficacy of early aggressive interventions in modifying the natural history of this disease.",
author = "Karim, {R. M.} and Khawaja, {H. A.} and S. Naz and Merchant, {S. S.} and Momin, {I. A.} and I. Lalani and Sewani, {Asif A.} and S. Akhtar and A. Ahmed",
year = "1999",
month = "6",
day = "1",
language = "English (US)",
volume = "49",
pages = "149--154",
journal = "JPMA. The Journal of the Pakistan Medical Association",
issn = "0030-9982",
publisher = "Pakistan Medical Association",
number = "6",

}

TY - JOUR

T1 - Q wave and non-Q wave myocardial infarction

T2 - a multivariate analysis of survival experience and clinical outcome after first diagnosis at a tertiary care hospital.

AU - Karim, R. M.

AU - Khawaja, H. A.

AU - Naz, S.

AU - Merchant, S. S.

AU - Momin, I. A.

AU - Lalani, I.

AU - Sewani, Asif A.

AU - Akhtar, S.

AU - Ahmed, A.

PY - 1999/6/1

Y1 - 1999/6/1

N2 - INTRODUCTION: Myocardial infarction (MI) is a well-recognized clinical entity with a worldwide distribution. In the United States alone, 1.5 million cases of MI occur per year. This study compares the in-hospital mortality, 1 year mortality and time to death following a first Q-wave or non Q-wave myocardial infarction (MI). METHODS: One thousand five hundred and ninety-six patients were admitted at the Aga Khan University Hospital with a diagnosis of MI over a period of four years of whom 420 patients met our inclusion criteria. Data was collected from the patients' medical records and on telephone using a pretested questionnaire. Logistic regression and Cox proportional hazard models were used to analyze the data. RESULTS: The mean age +/- sd of the patients was 59 +/- 10 years. Of the total patients, 151(36%) and 269(64%) suffered non-Q wave and Q-wave MI respectively. A higher in hospital mortality was observed in patients with Q-wave MI (n = 64, 23.8%) than those with non-Q wave MI [n = 16 (10.6%); adjusted OR = 2.76, 95% CI: 1.5-5.01]. Similarly, patients having Q-wave MI experienced increased 1 year mortality (n = 77, 28.6%) compared to patients suffering non-Q wave MI [n = 26 (17.2%); adjusted OR = 2.04, 95% CI: 1.21-3.43]. CONCLUSION: Patients with Q-wave MI had a worse prognosis compared with patients with non-Q-wave MI and therefore warrant a closer follow up. Further prospective studies are needed to evaluate the efficacy of early aggressive interventions in modifying the natural history of this disease.

AB - INTRODUCTION: Myocardial infarction (MI) is a well-recognized clinical entity with a worldwide distribution. In the United States alone, 1.5 million cases of MI occur per year. This study compares the in-hospital mortality, 1 year mortality and time to death following a first Q-wave or non Q-wave myocardial infarction (MI). METHODS: One thousand five hundred and ninety-six patients were admitted at the Aga Khan University Hospital with a diagnosis of MI over a period of four years of whom 420 patients met our inclusion criteria. Data was collected from the patients' medical records and on telephone using a pretested questionnaire. Logistic regression and Cox proportional hazard models were used to analyze the data. RESULTS: The mean age +/- sd of the patients was 59 +/- 10 years. Of the total patients, 151(36%) and 269(64%) suffered non-Q wave and Q-wave MI respectively. A higher in hospital mortality was observed in patients with Q-wave MI (n = 64, 23.8%) than those with non-Q wave MI [n = 16 (10.6%); adjusted OR = 2.76, 95% CI: 1.5-5.01]. Similarly, patients having Q-wave MI experienced increased 1 year mortality (n = 77, 28.6%) compared to patients suffering non-Q wave MI [n = 26 (17.2%); adjusted OR = 2.04, 95% CI: 1.21-3.43]. CONCLUSION: Patients with Q-wave MI had a worse prognosis compared with patients with non-Q-wave MI and therefore warrant a closer follow up. Further prospective studies are needed to evaluate the efficacy of early aggressive interventions in modifying the natural history of this disease.

UR - http://www.scopus.com/inward/record.url?scp=0033138927&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033138927&partnerID=8YFLogxK

M3 - Article

C2 - 10599199

AN - SCOPUS:0033138927

VL - 49

SP - 149

EP - 154

JO - JPMA. The Journal of the Pakistan Medical Association

JF - JPMA. The Journal of the Pakistan Medical Association

SN - 0030-9982

IS - 6

ER -