Qualitative assessment of pica experienced by frequent blood donors

Melanie C. Chansky, Melissa R. King, Walter Bialkowski, Barbara Bryant, Joseph E. Kiss, Pam D'Andrea, Ritchard G. Cable, Bryan R. Spencer, Alan E. Mast

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

BACKGROUND: Pica, the compulsive consumption of ice or other nonnutritious substances, is associated with iron deficiency, a common negative consequence of frequent blood donation. Because of this, blood donors, such as those participating in the Strategies to Reduce Iron Deficiency (STRIDE) study, are an ideal population to explore pica and iron deficiency. STUDY DESIGN AND METHODS: STRIDE was a 2-year intervention trial to assess the effectiveness of iron supplementation for mitigating iron deficiency in frequent blood donors. Subjects completed baseline and follow-up questionnaires that included questions about pica symptoms. In-depth telephone interviews were conducted with 14 of these subjects reporting pica symptoms and eight presumed controls (casual ice chewers) to gain a deeper understanding of pica symptoms and their impact on daily life and to make a final determination on the presence of pica. RESULTS: Pica was confirmed in five of the 14 subjects reporting symptoms and in two of eight controls. Outcome misclassification based on the questionnaire was attributed to inadequate assessment of several pica symptoms identified during the interview. Comparison of subjects' repeated quantitative iron measurements taken throughout STRIDE with subjects' final adjudicated pica status revealed a positive relationship between development of pica and worsening iron status; the opposite was found in those whose pica symptoms resolved. CONCLUSION: Continued refinement of pica symptom questions will allow for rapid and accurate detection of pica in frequent blood donors and confirmation of successful treatment with iron supplements.

Original languageEnglish (US)
Pages (from-to)946-951
Number of pages6
JournalTransfusion
Volume57
Issue number4
DOIs
StatePublished - Apr 1 2017
Externally publishedYes

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Pica
Blood Donors
Iron
Ice
Interviews

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Hematology

Cite this

Chansky, M. C., King, M. R., Bialkowski, W., Bryant, B., Kiss, J. E., D'Andrea, P., ... Mast, A. E. (2017). Qualitative assessment of pica experienced by frequent blood donors. Transfusion, 57(4), 946-951. https://doi.org/10.1111/trf.13981

Qualitative assessment of pica experienced by frequent blood donors. / Chansky, Melanie C.; King, Melissa R.; Bialkowski, Walter; Bryant, Barbara; Kiss, Joseph E.; D'Andrea, Pam; Cable, Ritchard G.; Spencer, Bryan R.; Mast, Alan E.

In: Transfusion, Vol. 57, No. 4, 01.04.2017, p. 946-951.

Research output: Contribution to journalArticle

Chansky, MC, King, MR, Bialkowski, W, Bryant, B, Kiss, JE, D'Andrea, P, Cable, RG, Spencer, BR & Mast, AE 2017, 'Qualitative assessment of pica experienced by frequent blood donors', Transfusion, vol. 57, no. 4, pp. 946-951. https://doi.org/10.1111/trf.13981
Chansky MC, King MR, Bialkowski W, Bryant B, Kiss JE, D'Andrea P et al. Qualitative assessment of pica experienced by frequent blood donors. Transfusion. 2017 Apr 1;57(4):946-951. https://doi.org/10.1111/trf.13981
Chansky, Melanie C. ; King, Melissa R. ; Bialkowski, Walter ; Bryant, Barbara ; Kiss, Joseph E. ; D'Andrea, Pam ; Cable, Ritchard G. ; Spencer, Bryan R. ; Mast, Alan E. / Qualitative assessment of pica experienced by frequent blood donors. In: Transfusion. 2017 ; Vol. 57, No. 4. pp. 946-951.
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