Quantitation of sprouting of dorsal root axons

Claire E. Hulsebosch, Richard E. Coggeshall

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations

    Abstract

    The axonal sprouting that occurs after denervation resulting from a spinal hemisection can be quantified. Rats were subjected to hemisection of the spinal cord at birth, and the myelinated and unmyelinated axons in dorsal roots three segments cranial and three segments caudal to the lesion were counted 1 month after surgery. The number of unmyelinated axons in the dorsal root on the side of the hemisection increased 22 percent for the roots one segment from the lesion and 13 percent for the roots two and three segments from the lesion.

    Original languageEnglish (US)
    Pages (from-to)1020-1021
    Number of pages2
    JournalScience
    Volume213
    Issue number4511
    DOIs
    StatePublished - 1981

    ASJC Scopus subject areas

    • General

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