Quinidine-Induced Thrombocytopenia With Pulmonary Hemorrhage

Jack B. Alperin, William J. Degroot, Philip L. Cimo

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Abstract

Examination of an elderly man with quinidine sulfateinduced thrombocytopenia complicated by pulmonary hemorrhage failed to identify any underlying pulmonary disease contributing to the bleeding. All bleeding ceased, and pulmonary infiltrates disappeared after the platelet count returned to normal. Special studies indicated a high titer quinidine-dependent IgG antibody level in the patient's serum and a strongly positive quinidine patch test result on his forearm. The pathogenesis of pulmonary hemorrhage is considered in view of these studies.

Original languageEnglish (US)
Pages (from-to)266-267
Number of pages2
JournalArchives of Internal Medicine
Volume140
Issue number2
DOIs
StatePublished - Feb 1980

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ASJC Scopus subject areas

  • Internal Medicine

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