Race and outcomes in gastroschisis repair

A nationwide analysis

Ye Kyung Song, Omar Nunez Lopez, Hemalkumar Mehta, Fredrick J. Bohanon, Yesenia Rojas-Khalil, Kanika Bowen-Jallow, Ravi Radhakrishnan

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: The incidence of gastroschisis has increased 30% between the periods 1995-2005 and 2006-2012, with the largest increase in Black neonates born to Black mothers younger than 20. years old. Objective: Racial disparities in peri- and post-operative outcomes have been previously identified in several types of adult and pediatric surgical patients. Is there an association between race and clinical outcomes and healthcare resource utilization in neonates with gastroschisis? Methods: Retrospective study using national administrative data from the Kid's Inpatient Database (KID) from 2006, 2009, and 2012 for neonates (age. <. 28. days) with gastroschisis. Multivariable logistic regression was constructed to determine the association of race and socioeconomic characteristics with complications and mortality; linear regression was used for length of stay and hospital charges. Results: We identified 3846 neonates with gastroschisis that underwent surgical repair, including 676 patients with complex gastroschisis. When controlling for birth weight, payer status, socioeconomic status, and hospital characteristics, Black neonates had increased odds of having complex gastroschisis and associated atresias. Mortality was higher in patients with complex gastroschisis, patients from the lowest income quartiles, and patients with Medicaid as primary payer (compared to those with private insurance). Length of stay (LOS) was increased in patients with complex gastroschisis, birth weight <. 2500. g, and Medicaid patients. Hospital charges were higher in complex gastroschisis, Black and Hispanic neonates (as compared to Whites), males, birth weight <. 2500. g, and Medicaid patients. Conclusions: There is an association between race and complex gastroschisis, associated intestinal atresias, and total charges in neonates with gastroschisis. In addition, income status is associated with mortality and hospital charges while payer status is associated with complications, mortality, LOS, and hospital charges. Public health and prenatal interventions should target at-risk populations to improve clinical outcomes. Prognosis Study: Level of Evidence: II.

Original languageEnglish (US)
JournalJournal of Pediatric Surgery
DOIs
StateAccepted/In press - Nov 12 2016

Fingerprint

Gastroschisis
Hospital Charges
Newborn Infant
Medicaid
Birth Weight
Length of Stay
Mortality
Intestinal Atresia
Insurance
Hispanic Americans
Social Class
Inpatients
Linear Models
Retrospective Studies
Public Health

Keywords

  • Gastroschisis
  • Health disparities
  • Outcomes
  • Pediatric surgery
  • Race

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Race and outcomes in gastroschisis repair : A nationwide analysis. / Song, Ye Kyung; Nunez Lopez, Omar; Mehta, Hemalkumar; Bohanon, Fredrick J.; Rojas-Khalil, Yesenia; Bowen-Jallow, Kanika; Radhakrishnan, Ravi.

In: Journal of Pediatric Surgery, 12.11.2016.

Research output: Contribution to journalArticle

Song, Ye Kyung ; Nunez Lopez, Omar ; Mehta, Hemalkumar ; Bohanon, Fredrick J. ; Rojas-Khalil, Yesenia ; Bowen-Jallow, Kanika ; Radhakrishnan, Ravi. / Race and outcomes in gastroschisis repair : A nationwide analysis. In: Journal of Pediatric Surgery. 2016.
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AU - Rojas-Khalil, Yesenia

AU - Bowen-Jallow, Kanika

AU - Radhakrishnan, Ravi

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N2 - Background: The incidence of gastroschisis has increased 30% between the periods 1995-2005 and 2006-2012, with the largest increase in Black neonates born to Black mothers younger than 20. years old. Objective: Racial disparities in peri- and post-operative outcomes have been previously identified in several types of adult and pediatric surgical patients. Is there an association between race and clinical outcomes and healthcare resource utilization in neonates with gastroschisis? Methods: Retrospective study using national administrative data from the Kid's Inpatient Database (KID) from 2006, 2009, and 2012 for neonates (age. <. 28. days) with gastroschisis. Multivariable logistic regression was constructed to determine the association of race and socioeconomic characteristics with complications and mortality; linear regression was used for length of stay and hospital charges. Results: We identified 3846 neonates with gastroschisis that underwent surgical repair, including 676 patients with complex gastroschisis. When controlling for birth weight, payer status, socioeconomic status, and hospital characteristics, Black neonates had increased odds of having complex gastroschisis and associated atresias. Mortality was higher in patients with complex gastroschisis, patients from the lowest income quartiles, and patients with Medicaid as primary payer (compared to those with private insurance). Length of stay (LOS) was increased in patients with complex gastroschisis, birth weight <. 2500. g, and Medicaid patients. Hospital charges were higher in complex gastroschisis, Black and Hispanic neonates (as compared to Whites), males, birth weight <. 2500. g, and Medicaid patients. Conclusions: There is an association between race and complex gastroschisis, associated intestinal atresias, and total charges in neonates with gastroschisis. In addition, income status is associated with mortality and hospital charges while payer status is associated with complications, mortality, LOS, and hospital charges. Public health and prenatal interventions should target at-risk populations to improve clinical outcomes. Prognosis Study: Level of Evidence: II.

AB - Background: The incidence of gastroschisis has increased 30% between the periods 1995-2005 and 2006-2012, with the largest increase in Black neonates born to Black mothers younger than 20. years old. Objective: Racial disparities in peri- and post-operative outcomes have been previously identified in several types of adult and pediatric surgical patients. Is there an association between race and clinical outcomes and healthcare resource utilization in neonates with gastroschisis? Methods: Retrospective study using national administrative data from the Kid's Inpatient Database (KID) from 2006, 2009, and 2012 for neonates (age. <. 28. days) with gastroschisis. Multivariable logistic regression was constructed to determine the association of race and socioeconomic characteristics with complications and mortality; linear regression was used for length of stay and hospital charges. Results: We identified 3846 neonates with gastroschisis that underwent surgical repair, including 676 patients with complex gastroschisis. When controlling for birth weight, payer status, socioeconomic status, and hospital characteristics, Black neonates had increased odds of having complex gastroschisis and associated atresias. Mortality was higher in patients with complex gastroschisis, patients from the lowest income quartiles, and patients with Medicaid as primary payer (compared to those with private insurance). Length of stay (LOS) was increased in patients with complex gastroschisis, birth weight <. 2500. g, and Medicaid patients. Hospital charges were higher in complex gastroschisis, Black and Hispanic neonates (as compared to Whites), males, birth weight <. 2500. g, and Medicaid patients. Conclusions: There is an association between race and complex gastroschisis, associated intestinal atresias, and total charges in neonates with gastroschisis. In addition, income status is associated with mortality and hospital charges while payer status is associated with complications, mortality, LOS, and hospital charges. Public health and prenatal interventions should target at-risk populations to improve clinical outcomes. Prognosis Study: Level of Evidence: II.

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