Racial difference in lean mass distribution among reproductive-aged women

Mahbubur Rahman, Abbey B. Berenson

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Objective: Lean mass is an important determinant of bone mineral density (BMD) accrual, yet data regarding its correlates based on multiethnic premenopausal women are lacking. We examined the influence of age, race/ethnicity, and lifestyle variables on total and regional lean mass distribution in this population. Design: A cross-sectional study was conducted on 708 healthy Black, White, and Hispanic women aged 16-33 years who were seen in an outpatient clinic. In addition, 218 of these women were followed for up to 36 months to observe changes in the relevant variables. We measured body weight, height, and lean mass distribution using a digital scale, wall-mounted stadiometer, and dual-energy absorptiometry (DXA), respectively. Multiple linear regression and mixed-model regression analyses were used to model the relationship of age, race/ethnicity and lifestyle variables to total and regional lean mass. Results: For a given body mass index (BMI), Black women had higher total body lean mass (LMtotal) and leg lean mass (LM leg) than White and Hispanic women. Hispanic women had significantly lower LMtotal, trunk lean mass (LMtrunk), and LM leg than Black and White women. The difference between Blacks and Whites with regard to LMtotal significantly magnified with increasing BMI. Weight-bearing exercise and age at menarche were positively associated with lean mass variables, while parity was negatively associated with LM leg. LMtotal and LMtrunk increased over 36 months. Calcium intake was positively associated with increase in LM total over time. Conclusions: Our study shows that racial differences exist in the distribution of lean mass for a given BMI among reproductive-aged women.

Original languageEnglish (US)
Pages (from-to)346-352
Number of pages7
JournalEthnicity and Disease
Volume20
Issue number4
StatePublished - Sep 2010

Keywords

  • Bone mineral density
  • Lean mass
  • Racial differences
  • Reproductive-aged women

ASJC Scopus subject areas

  • Epidemiology

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