Radiofrequency ablation of Barrett's esophagus

G. Arora, S. Basra, A. K. Roorda, George Triadafilopoulos

Research output: Contribution to journalReview article

17 Scopus citations

Abstract

Background: Barrett's esophagus (BE) is an important risk factor for esophageal carcinoma and its incidence is likely rising. Amongst the various available endoscopic ablative therapies, radiofrequency ablation (RFA) is a very promising new one. Methods: We performed a comprehensive review of the literature on the treatment of BE using RFA. We searched for published articles on Pubmed and also reviewed the abstracts from the major gastroenterological society meetings of 2007 and 2008. Results: RFA is an effective option in treating BE, especially when dysplastic changes are present, achieving high eradication rates with minimal complications. Prior control of intra-esophageal pH by either armacologic therapy or fundoplication is important in maximizing ef-ficacy and preventing relapse. Conclusions: RFA is a very well tolerated therapy for non-dysplastic and dysplastic BE and will likely become a first-line treatment.More data, however, will be needed to compare the various existing modalities of endoscopic ablative and resection therapies for BE.

Original languageEnglish (US)
Pages (from-to)19-25
Number of pages7
JournalEuropean Surgery - Acta Chirurgica Austriaca
Volume41
Issue number1
DOIs
StatePublished - Mar 19 2009

Keywords

  • Ablation
  • Barrett's
  • Radiofrequency

ASJC Scopus subject areas

  • Surgery

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