Rational design, conformational studies and bioactivity of highly potent conformationally constrained calcitonin analogues

Keyphrases

• Conformationally Constrained 100%
• Calcitonin 100%
• Rational Design 100%
• Bioactivity 100%
• Conformational Study 100%
• Human Calcitonin 100%
• High Potency 10%
• Osteoporosis Treatment 10%
• Amino Acid Residues 5%
• Bone Resorption 5%
• In Vivo Efficacy 5%
• Side Chain 5%
• Bicyclol 5%
• Far-UV CD 5%
• CD Spectra 5%
• Lead Structure 5%
• Salmon Calcitonin 5%
• Novel Leads 5%
• Conformational Characteristics 5%
• Bone Disorders 5%
• Ring Width 5%
• Osteoporosis Disease 5%
• Paget's Disease 5%
• In Vivo Bioactivity 5%
• Topological Features 5%
• Bioactive Conformation 5%

Biochemistry, Genetics and Molecular Biology

• Calcitonin 100%
• Biological Activity 100%
• Conformation 18%
• Amino Acids 4%
• Osteolysis 4%
• Salmonine 4%
• Salmon 4%

Pharmacology, Toxicology and Pharmaceutical Science

• Calcitonin 100%
• Calcitonin Derivative 100%
• Diseases 10%
• Amino Acid 5%
• Salcatonin 5%
• Methyl Yellow 5%
• Bone Disease 5%