Rational Design of Hit Compounds TargetingStaphylococcus aureusThreonyl-tRNA Synthetase

Keyphrases

• Molecular Targets 100%
• Rational Design 100%
• TRNA Synthetase 100%
• Hit Compound 100%
• Soluble Form 50%
• Medicinal Chemistry 50%
• Recombinant 50%
• Infectious Diseases 50%
• Antibiotics 50%
• Inhibitory Activity 50%
• Chemical Classes 50%
• Screening Assays 50%
• Nitro 50%
• Eukaryotic Cells 50%
• Therapeutic Regimen 50%
• Aminoacyl-tRNA Synthetase 50%
• EC50 50%
• Phenyl 50%
• HEK293 50%
• Compound II 50%
• Current Therapeutics 50%
• Nosocomial Pathogens 50%
• Novel Mechanism of Action 50%
• Multidrug Resistance 50%
• Staphylococcal Infections 50%
• Thiazol 50%
• Molecular Docking 50%
• Hospital-acquired 50%
• Active Compounds 50%
• Inhibitor Screening 50%
• Biological Research 50%
• Optimization Research 50%
• Antibiotic Development 50%
• Superbugs 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Amino Acid Transfer RNA Ligase 100%
• Molecular Target 66%
• Infectious Agent 33%
• Antibiotics 33%
• Pharmaceutical Chemistry 33%
• Staphylococcal Infection 33%
• EC50 33%
• Phenol 33%
• Multidrug Resistance 33%
• Diseases 33%