Reactive Oxygen Species (ROS) are Critical for Morphine Exacerbation of HIV-1 gp120-Induced Pain

Keyphrases

• Reactive Oxygen Species 100%
• Gp120 100%
• Morphine 100%
• Evoked Pain 100%
• Spinal Dorsal Horn 40%
• Chronic Use 40%
• Opioid Analgesics 40%
• Inflammatory Cytokines 20%
• Mouse Model 20%
• HIV Patients 20%
• Interleukin-1β 20%
• Analgesic 20%
• Mitochondrial Reactive Oxygen Species (mtROS) 20%
• Clinical Practice 20%
• Chronic Pain 20%
• Pain States 20%
• Pathogenic Mechanism 20%
• Opioids 20%
• Hyperalgesia 20%
• Molecular Pathways 20%
• Clinical Evidence 20%
• Astrocytes 20%
• HIV-associated 20%
• HIV Pain 20%
• Astrocyte Activation 20%
• Systemic Application 20%
• Morphine Treatment 20%
• Tert-butyl 20%
• Pain Models 20%
• Reactive Oxygen Species Scavenger 20%
• Phenyl 20%
• Cellular Pathways 20%
• Nitrones 20%
• Negative Impact 20%
• Astrocytic Activation 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Reactive Oxygen Metabolite 100%
• HIV 100%
• Morphine 100%
• Cytokine 33%
• Narcotic Analgesic Agent 33%
• Side Effect 16%
• Mouse Model 16%
• Opiate 16%
• Tumor Necrosis Factor 16%
• Analgesic Agent 16%
• Chronic Pain 16%
• Hyperalgesia 16%
• Nitrone 16%

Neuroscience

• Human Immunodeficiency Virus 100%
• Morphine 100%
• Reactive Oxygen Species 100%
• Opiate 50%
• Astrocyte 33%
• Analgesic 33%
• Proinflammatory Cytokine 16%
• Hyperalgesia 16%