Recent Advances in Burkholderia mallei and B. pseudomallei Research

Christopher L. Hatcher, Laura A. Muruato, Alfredo G. Torres

Research output: Contribution to journalReview article

28 Scopus citations

Abstract

Burkholderia mallei and Burkholderia pseudomallei are Gram-negative organisms, which are etiological agents of glanders and melioidosis, respectively. Although only B. pseudomallei is responsible for a significant number of human cases, both organisms are classified as Tier 1 Select Agents and their diseases lack effective diagnosis and treatment. Despite a recent resurgence in research pertaining to these organisms, there are still a number of knowledge gaps. This article summarizes the latest research progress in the fields of B. mallei and B. pseudomallei pathogenesis, vaccines, and diagnostics.

Original languageEnglish (US)
Pages (from-to)62-69
Number of pages8
JournalCurrent Tropical Medicine Reports
Volume2
Issue number2
DOIs
StatePublished - Jun 1 2015

Keywords

  • B. mallei
  • B. pseudomallei
  • Diagnostics
  • Glanders
  • Melioidosis
  • Pathogenesis
  • Vaccines

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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