Recent advances in Canavan disease.

R. Matalon, K. Michals-Matalon

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations


More studies are needed to elucidate the pathophysiology of Canavan disease and how the inability to hydrolyze NAA leads to spongy degeneration. The creation of an animal model would be helpful in the understanding of the disease and the formulation of gene therapy.

Original languageEnglish (US)
Pages (from-to)493-506
Number of pages14
JournalAdvances in pediatrics
StatePublished - 1999

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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