Recent advances in understanding West Nile virus host immunity and viral pathogenesis

Tian Wang, Huanle Luo

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

West Nile virus (WNV), a mosquito-borne flavivirus, has been a significant public health concern in the United States for nearly two decades. The virus has been linked to acute viral encephalitis, neurological sequelae, and chronic kidney diseases. Neither antiviral drugs nor vaccines are currently available for humans. In vitro cell culture and experimental animal models have been used to study WNV infection in humans. In this review, we will focus on recent findings and provide new insights into WNV host immunity and viral pathogenesis.

Original languageEnglish (US)
Article number338
JournalF1000Research
Volume7
DOIs
StatePublished - Jan 1 2018

Fingerprint

West Nile virus
Viruses
Immunity
Viral Encephalitis
Flavivirus
Virus Diseases
Culicidae
Chronic Renal Insufficiency
Antiviral Agents
Public health
Vaccines
Animal Models
Public Health
Cell Culture Techniques
Cell culture
Animals

Keywords

  • Animal models
  • Host Immunity
  • Pathogenesis
  • West Nile Virus

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Recent advances in understanding West Nile virus host immunity and viral pathogenesis. / Wang, Tian; Luo, Huanle.

In: F1000Research, Vol. 7, 338, 01.01.2018.

Research output: Contribution to journalReview article

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