Recent advances in understanding West Nile virus host immunity and viral pathogenesis

Tian Wang, Huanle Luo

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations

Abstract

West Nile virus (WNV), a mosquito-borne flavivirus, has been a significant public health concern in the United States for nearly two decades. The virus has been linked to acute viral encephalitis, neurological sequelae, and chronic kidney diseases. Neither antiviral drugs nor vaccines are currently available for humans. In vitro cell culture and experimental animal models have been used to study WNV infection in humans. In this review, we will focus on recent findings and provide new insights into WNV host immunity and viral pathogenesis.

Original languageEnglish (US)
Article number338
JournalF1000Research
Volume7
DOIs
StatePublished - 2018

Keywords

  • Animal models
  • Host Immunity
  • Pathogenesis
  • West Nile Virus

ASJC Scopus subject areas

  • General Immunology and Microbiology
  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology

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