Recent developments in West Nile virus vaccine and antiviral therapy

Anh N. Woodmansee, Pei-Yong Shi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

West Nile virus (WNV) is a mosquito-borne flavivirus that is now posing a severe threat to public health in North America. Prevention and treatment of WNV and other emerging flaviviruses represent a global public health priority. This article will review (i) general features of WNV transmission and replication (ii) strategies recently reported in the literature and patents for vaccine development against WNV infections and (iii) inhibitors reported to have anti-WNV activities. A number of approaches for antiviral drug discovery as well as strategies for improvement of the diagnosis of WNV infections are also suggested.

Original languageEnglish (US)
Pages (from-to)1113-1125
Number of pages13
JournalExpert Opinion on Therapeutic Patents
Volume13
Issue number8
DOIs
StatePublished - Aug 1 2003
Externally publishedYes

Fingerprint

West Nile Virus Vaccines
Active Immunotherapy
West Nile virus
Antiviral Agents
public health
patent
Flavivirus
Virus Diseases
threat
drug
Public Health
Health Priorities
Patents
Drug Discovery
Virus Replication
North America
Culicidae
Vaccines

Keywords

  • Antiviral therapy
  • Arbovirus
  • Clinical diagnosis
  • Flavivirus
  • Vaccine
  • West Nile virus

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Pharmacology
  • Law

Cite this

Recent developments in West Nile virus vaccine and antiviral therapy. / Woodmansee, Anh N.; Shi, Pei-Yong.

In: Expert Opinion on Therapeutic Patents, Vol. 13, No. 8, 01.08.2003, p. 1113-1125.

Research output: Contribution to journalArticle

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