Receptive fields of unmyelinated ventral root afferent fibres in the cat

G. L. Clifton, R. E. Coggeshall, W. H. Vance, W. D. Willis

Research output: Contribution to journalArticle

112 Citations (Scopus)

Abstract

The receptive fields were determined for 118 afferent fibres in the S2, S3 and Ca (caudal) 1 ventral roots of the cat. Of these fibres, ninety three were unmyelinated, another eleven were probably unmyelinated, and fourteen were myelinated, according to estimates of their conduction velocities. Confirmation that the recordings were from ventral root filaments came from electron microscopic inspection of ten of the filaments from which recordings of the activity of unmyelinated afferents were made. Receptive fields were demonstrated for twelve unmyelinated afferent fibres in the distal stumps of the S2 and S3 ventral roots which had been sectioned 3 weeks previously, indicating that the cell bodies giving rise to these fibres were not in the spinal cord. The action potentials of some of the unmyelinated ventral root afferent fibres were complex, suggesting branching of the afferents within the ventral root. One third of the unmyelinated ventral root afferents had receptive fields in somatic structures: the skin and deep tissues. Two thirds of the unmyelinated ventral root afferents had receptive fields in the viscera of the pelvis: the bladder, urethra, vagina and lower bowel. Many of the unmyelinated afferents in the ventral roots, especially those with cutaneous receptive fields, had high thresholds and may participate in nociception. It is concluded that the cat ventral root contains a major sensory component and that the Law of Bell and Magendie is not an accurate description of the organization of the ventral root in this animal.

Original languageEnglish (US)
Pages (from-to)573-600
Number of pages28
JournalJournal of Physiology
Volume256
Issue number3
StatePublished - 1976
Externally publishedYes

Fingerprint

Spinal Nerve Roots
Cats
Skin
Nociception
Viscera
Vagina
Urethra
Pelvis
Action Potentials
Spinal Cord
Urinary Bladder
Electrons

ASJC Scopus subject areas

  • Physiology

Cite this

Clifton, G. L., Coggeshall, R. E., Vance, W. H., & Willis, W. D. (1976). Receptive fields of unmyelinated ventral root afferent fibres in the cat. Journal of Physiology, 256(3), 573-600.

Receptive fields of unmyelinated ventral root afferent fibres in the cat. / Clifton, G. L.; Coggeshall, R. E.; Vance, W. H.; Willis, W. D.

In: Journal of Physiology, Vol. 256, No. 3, 1976, p. 573-600.

Research output: Contribution to journalArticle

Clifton, GL, Coggeshall, RE, Vance, WH & Willis, WD 1976, 'Receptive fields of unmyelinated ventral root afferent fibres in the cat', Journal of Physiology, vol. 256, no. 3, pp. 573-600.
Clifton GL, Coggeshall RE, Vance WH, Willis WD. Receptive fields of unmyelinated ventral root afferent fibres in the cat. Journal of Physiology. 1976;256(3):573-600.
Clifton, G. L. ; Coggeshall, R. E. ; Vance, W. H. ; Willis, W. D. / Receptive fields of unmyelinated ventral root afferent fibres in the cat. In: Journal of Physiology. 1976 ; Vol. 256, No. 3. pp. 573-600.
@article{967a67f30de640b8bb2b441d43ef906c,
title = "Receptive fields of unmyelinated ventral root afferent fibres in the cat",
abstract = "The receptive fields were determined for 118 afferent fibres in the S2, S3 and Ca (caudal) 1 ventral roots of the cat. Of these fibres, ninety three were unmyelinated, another eleven were probably unmyelinated, and fourteen were myelinated, according to estimates of their conduction velocities. Confirmation that the recordings were from ventral root filaments came from electron microscopic inspection of ten of the filaments from which recordings of the activity of unmyelinated afferents were made. Receptive fields were demonstrated for twelve unmyelinated afferent fibres in the distal stumps of the S2 and S3 ventral roots which had been sectioned 3 weeks previously, indicating that the cell bodies giving rise to these fibres were not in the spinal cord. The action potentials of some of the unmyelinated ventral root afferent fibres were complex, suggesting branching of the afferents within the ventral root. One third of the unmyelinated ventral root afferents had receptive fields in somatic structures: the skin and deep tissues. Two thirds of the unmyelinated ventral root afferents had receptive fields in the viscera of the pelvis: the bladder, urethra, vagina and lower bowel. Many of the unmyelinated afferents in the ventral roots, especially those with cutaneous receptive fields, had high thresholds and may participate in nociception. It is concluded that the cat ventral root contains a major sensory component and that the Law of Bell and Magendie is not an accurate description of the organization of the ventral root in this animal.",
author = "Clifton, {G. L.} and Coggeshall, {R. E.} and Vance, {W. H.} and Willis, {W. D.}",
year = "1976",
language = "English (US)",
volume = "256",
pages = "573--600",
journal = "Journal of Physiology",
issn = "0022-3751",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Receptive fields of unmyelinated ventral root afferent fibres in the cat

AU - Clifton, G. L.

AU - Coggeshall, R. E.

AU - Vance, W. H.

AU - Willis, W. D.

PY - 1976

Y1 - 1976

N2 - The receptive fields were determined for 118 afferent fibres in the S2, S3 and Ca (caudal) 1 ventral roots of the cat. Of these fibres, ninety three were unmyelinated, another eleven were probably unmyelinated, and fourteen were myelinated, according to estimates of their conduction velocities. Confirmation that the recordings were from ventral root filaments came from electron microscopic inspection of ten of the filaments from which recordings of the activity of unmyelinated afferents were made. Receptive fields were demonstrated for twelve unmyelinated afferent fibres in the distal stumps of the S2 and S3 ventral roots which had been sectioned 3 weeks previously, indicating that the cell bodies giving rise to these fibres were not in the spinal cord. The action potentials of some of the unmyelinated ventral root afferent fibres were complex, suggesting branching of the afferents within the ventral root. One third of the unmyelinated ventral root afferents had receptive fields in somatic structures: the skin and deep tissues. Two thirds of the unmyelinated ventral root afferents had receptive fields in the viscera of the pelvis: the bladder, urethra, vagina and lower bowel. Many of the unmyelinated afferents in the ventral roots, especially those with cutaneous receptive fields, had high thresholds and may participate in nociception. It is concluded that the cat ventral root contains a major sensory component and that the Law of Bell and Magendie is not an accurate description of the organization of the ventral root in this animal.

AB - The receptive fields were determined for 118 afferent fibres in the S2, S3 and Ca (caudal) 1 ventral roots of the cat. Of these fibres, ninety three were unmyelinated, another eleven were probably unmyelinated, and fourteen were myelinated, according to estimates of their conduction velocities. Confirmation that the recordings were from ventral root filaments came from electron microscopic inspection of ten of the filaments from which recordings of the activity of unmyelinated afferents were made. Receptive fields were demonstrated for twelve unmyelinated afferent fibres in the distal stumps of the S2 and S3 ventral roots which had been sectioned 3 weeks previously, indicating that the cell bodies giving rise to these fibres were not in the spinal cord. The action potentials of some of the unmyelinated ventral root afferent fibres were complex, suggesting branching of the afferents within the ventral root. One third of the unmyelinated ventral root afferents had receptive fields in somatic structures: the skin and deep tissues. Two thirds of the unmyelinated ventral root afferents had receptive fields in the viscera of the pelvis: the bladder, urethra, vagina and lower bowel. Many of the unmyelinated afferents in the ventral roots, especially those with cutaneous receptive fields, had high thresholds and may participate in nociception. It is concluded that the cat ventral root contains a major sensory component and that the Law of Bell and Magendie is not an accurate description of the organization of the ventral root in this animal.

UR - http://www.scopus.com/inward/record.url?scp=0017236897&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017236897&partnerID=8YFLogxK

M3 - Article

C2 - 944774

AN - SCOPUS:0017236897

VL - 256

SP - 573

EP - 600

JO - Journal of Physiology

JF - Journal of Physiology

SN - 0022-3751

IS - 3

ER -