Reconstruction of full-thickness defects with bovine-derived collagen/elastin matrix

A series of challenging cases and the first reported post-burn facial reconstruction

Josef Haik, Oren Weissman, Gabriel Hundeshagen, Nimrod Farber, Moti Harats, Shira M. Rozenblatt, Lars Peter Kamolz, Eyal Winkler, Isaac Zilinsky

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Reconstruction of full-thickness defects may benefit from integration of dermal substitutes, which serve as a foundation for split-thickness skin grafts, thus enhancing short and long-term results. We present a series of 7 patients who were treated between 2010 and 2012 for complicated full-thickness defects by the second-generation collagen/elastin matrix Matriderm® covered by a split-thickness skin graft. The defects resulted from malignancy resection, trauma, and post-burn scar reconstruction. Overall graft take was excellent and no complications were noted regarding the dermal substitute. Graft quality was close to normal skin in terms of elasticity, pliability, texture, and color. Good contour and cushioning of defects in weight bearing areas was also achieved. Matriderm was found to be a useful adjunct to full-thickness defect reconstruction, especially in difficult areas where the desired result is a scar of the highest quality possible.

Original languageEnglish (US)
Pages (from-to)866-868
Number of pages3
JournalJournal of Drugs in Dermatology
Volume11
Issue number7
StatePublished - Jul 2012
Externally publishedYes

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Elastin
Burns
Collagen
Artificial Skin
Transplants
Skin
Cicatrix
Elasticity
Weight-Bearing
Pliability
Color
Wounds and Injuries
Neoplasms
matriderm

ASJC Scopus subject areas

  • Dermatology

Cite this

Reconstruction of full-thickness defects with bovine-derived collagen/elastin matrix : A series of challenging cases and the first reported post-burn facial reconstruction. / Haik, Josef; Weissman, Oren; Hundeshagen, Gabriel; Farber, Nimrod; Harats, Moti; Rozenblatt, Shira M.; Kamolz, Lars Peter; Winkler, Eyal; Zilinsky, Isaac.

In: Journal of Drugs in Dermatology, Vol. 11, No. 7, 07.2012, p. 866-868.

Research output: Contribution to journalArticle

Haik, J, Weissman, O, Hundeshagen, G, Farber, N, Harats, M, Rozenblatt, SM, Kamolz, LP, Winkler, E & Zilinsky, I 2012, 'Reconstruction of full-thickness defects with bovine-derived collagen/elastin matrix: A series of challenging cases and the first reported post-burn facial reconstruction', Journal of Drugs in Dermatology, vol. 11, no. 7, pp. 866-868.
Haik, Josef ; Weissman, Oren ; Hundeshagen, Gabriel ; Farber, Nimrod ; Harats, Moti ; Rozenblatt, Shira M. ; Kamolz, Lars Peter ; Winkler, Eyal ; Zilinsky, Isaac. / Reconstruction of full-thickness defects with bovine-derived collagen/elastin matrix : A series of challenging cases and the first reported post-burn facial reconstruction. In: Journal of Drugs in Dermatology. 2012 ; Vol. 11, No. 7. pp. 866-868.
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