Recruitment of patients for a clinical trial

Factors on the physician side and reasons on the patient side

Tsuguya Fukui, Mahbubur Rahman, Takuro Shimbo, Satoshi Morita, Junichi Sakamoto

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objectives: To examine the factors related to actual patient recruiters among the physicians who initially agreed to collaborate in a randomized control trial. Methods: We conducted a questionnaire survey of 679 physicians (512 actual recruiter and 167 non-recruiters) who had initially agreed to recruit patients for a clinical trial to determine factors to predict who would actually do so. Results: Response rates among recruiters and non-recruiters were 87.5% and 73.1%, respectively. Multivariate logistic regression model showed that the proportions of regular users of computer [odds ratio (OR) =2.1, 95% confidence intervals (CI)=1.3-3.3] (p=0.002) and current participants in other clinical trials (OR=2.2, CI=1.5-3.4) (p=0.001) were significantly higher among recruiters than non-recruiters. Patients' reasons for non-participation as perceived by the physicians did not differ between recruiters and non-recruiters. Conclusion: Results of this study might be useful in predicting actual recruiters at the outset of clinical trials.

Original languageEnglish (US)
Pages (from-to)511-514
Number of pages4
JournalInternal Medicine
Volume45
Issue number8
DOIs
StatePublished - May 15 2006
Externally publishedYes

Fingerprint

Patient Selection
Clinical Trials
Physicians
Logistic Models
Odds Ratio
Confidence Intervals
Surveys and Questionnaires

Keywords

  • Japan
  • Patient recruitment
  • Physician participation
  • Randomized controlled trial

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Recruitment of patients for a clinical trial : Factors on the physician side and reasons on the patient side. / Fukui, Tsuguya; Rahman, Mahbubur; Shimbo, Takuro; Morita, Satoshi; Sakamoto, Junichi.

In: Internal Medicine, Vol. 45, No. 8, 15.05.2006, p. 511-514.

Research output: Contribution to journalArticle

Fukui, Tsuguya ; Rahman, Mahbubur ; Shimbo, Takuro ; Morita, Satoshi ; Sakamoto, Junichi. / Recruitment of patients for a clinical trial : Factors on the physician side and reasons on the patient side. In: Internal Medicine. 2006 ; Vol. 45, No. 8. pp. 511-514.
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