Recurrencia de la infeccióngástrica con Helicobacter pylori en adultos peruanos con distrés postprandial dos años después de la erradicaciónexitosa

Italo Novoa Reyes; María Caravedo Martínez; Jorge Huerta-Mercado Tenorio; Raúl De los Ríos Senmache; José Pinto Valdivia; Alejandro Bussalleu Rivera

Recurrencia de la infeccióngástrica con Helicobacter pylori en adultos peruanos con distrés postprandial dos años después de la erradicaciónexitosa

Translated title of the contribution: Recurrence rate of Helicobacter pylori infection two years after successful eradication in Peruvian patients presenting with postprandial distress syndrome

Italo Novoa Reyes, María Caravedo Martínez, Jorge Huerta-Mercado Tenorio, Raúl De los Ríos Senmache, José Pinto Valdivia, Alejandro Bussalleu Rivera

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

INTRODUCTION: The general reported recurrence rate of H. pylori infection in Peru is high, implying that the long term effectiveness of anti H. pylori therapy is lower than expected. This would lead to an increase in the prevalence of gastric cancer and other associated pathologies.

MATERIALS AND METHODS: This is a prospective cohort study including Peruvian patients with postprandial distress and H. pylori infection confirmed by gastric biopsy who recieved treatment and achieved bacterial eradication. Two years after the initial diagnosis, patients were contacted to determine the recurrence rate of H. pylori infection through the Urea breath test.

RESULTS: 101 /129 of the patients that were infected with H. pylori had a successful eradication of the infection and 28/129 failed to eradicate the bacteria. The effectiveness rate of treatment was 77.2%. Two years after successful eradication we were able to contact 65/101 participants, 5 of them presented positive urea breath tests (recurrence rate of infection of 7.7%) (IC 1.5%-13.5%, α = 0.05). The annual recurrence rate was 3.85% per year/ patient. 94% of the patients in the cohort came from poor city areas, 95.4% had drinking water at home and 90.8% drank boiled drinking water on a daily basis.

CONCLUSIONS: The recurrence rate of H. pylori in some populations of Peru is lower than expected and comparable with developed countries.

Translated title of the contribution	Recurrence rate of Helicobacter pylori infection two years after successful eradication in Peruvian patients presenting with postprandial distress syndrome
Original language	Spanish
Pages (from-to)	15-21
Number of pages	7
Journal	Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
Volume	34
Issue number	1
State	Published - Jan 1 2014
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Cite this

Novoa Reyes, I., Caravedo Martínez, M., Huerta-Mercado Tenorio, J., De los Ríos Senmache, R., Pinto Valdivia, J., & Bussalleu Rivera, A. (2014). Recurrencia de la infeccióngástrica con Helicobacter pylori en adultos peruanos con distrés postprandial dos años después de la erradicaciónexitosa. Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú, 34(1), 15-21.

Recurrencia de la infeccióngástrica con Helicobacter pylori en adultos peruanos con distrés postprandial dos años después de la erradicaciónexitosa. / Novoa Reyes, Italo; Caravedo Martínez, María; Huerta-Mercado Tenorio, Jorge et al.
In: Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú, Vol. 34, No. 1, 01.01.2014, p. 15-21.

Research output: Contribution to journal › Article › peer-review

Novoa Reyes, I, Caravedo Martínez, M, Huerta-Mercado Tenorio, J, De los Ríos Senmache, R, Pinto Valdivia, J & Bussalleu Rivera, A 2014, 'Recurrencia de la infeccióngástrica con Helicobacter pylori en adultos peruanos con distrés postprandial dos años después de la erradicaciónexitosa', Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú, vol. 34, no. 1, pp. 15-21.

Novoa Reyes I, Caravedo Martínez M, Huerta-Mercado Tenorio J, De los Ríos Senmache R, Pinto Valdivia J, Bussalleu Rivera A. Recurrencia de la infeccióngástrica con Helicobacter pylori en adultos peruanos con distrés postprandial dos años después de la erradicaciónexitosa. Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú. 2014 Jan 1;34(1):15-21.

Novoa Reyes, Italo ; Caravedo Martínez, María ; Huerta-Mercado Tenorio, Jorge et al. / Recurrencia de la infeccióngástrica con Helicobacter pylori en adultos peruanos con distrés postprandial dos años después de la erradicaciónexitosa. In: Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú. 2014 ; Vol. 34, No. 1. pp. 15-21.

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abstract = "INTRODUCTION: The general reported recurrence rate of H. pylori infection in Peru is high, implying that the long term effectiveness of anti H. pylori therapy is lower than expected. This would lead to an increase in the prevalence of gastric cancer and other associated pathologies.MATERIALS AND METHODS: This is a prospective cohort study including Peruvian patients with postprandial distress and H. pylori infection confirmed by gastric biopsy who recieved treatment and achieved bacterial eradication. Two years after the initial diagnosis, patients were contacted to determine the recurrence rate of H. pylori infection through the Urea breath test.RESULTS: 101 /129 of the patients that were infected with H. pylori had a successful eradication of the infection and 28/129 failed to eradicate the bacteria. The effectiveness rate of treatment was 77.2%. Two years after successful eradication we were able to contact 65/101 participants, 5 of them presented positive urea breath tests (recurrence rate of infection of 7.7%) (IC 1.5%-13.5%, α = 0.05). The annual recurrence rate was 3.85% per year/ patient. 94% of the patients in the cohort came from poor city areas, 95.4% had drinking water at home and 90.8% drank boiled drinking water on a daily basis.CONCLUSIONS: The recurrence rate of H. pylori in some populations of Peru is lower than expected and comparable with developed countries.",

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AU - Huerta-Mercado Tenorio, Jorge

AU - De los Ríos Senmache, Raúl

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N2 - INTRODUCTION: The general reported recurrence rate of H. pylori infection in Peru is high, implying that the long term effectiveness of anti H. pylori therapy is lower than expected. This would lead to an increase in the prevalence of gastric cancer and other associated pathologies.MATERIALS AND METHODS: This is a prospective cohort study including Peruvian patients with postprandial distress and H. pylori infection confirmed by gastric biopsy who recieved treatment and achieved bacterial eradication. Two years after the initial diagnosis, patients were contacted to determine the recurrence rate of H. pylori infection through the Urea breath test.RESULTS: 101 /129 of the patients that were infected with H. pylori had a successful eradication of the infection and 28/129 failed to eradicate the bacteria. The effectiveness rate of treatment was 77.2%. Two years after successful eradication we were able to contact 65/101 participants, 5 of them presented positive urea breath tests (recurrence rate of infection of 7.7%) (IC 1.5%-13.5%, α = 0.05). The annual recurrence rate was 3.85% per year/ patient. 94% of the patients in the cohort came from poor city areas, 95.4% had drinking water at home and 90.8% drank boiled drinking water on a daily basis.CONCLUSIONS: The recurrence rate of H. pylori in some populations of Peru is lower than expected and comparable with developed countries.

AB - INTRODUCTION: The general reported recurrence rate of H. pylori infection in Peru is high, implying that the long term effectiveness of anti H. pylori therapy is lower than expected. This would lead to an increase in the prevalence of gastric cancer and other associated pathologies.MATERIALS AND METHODS: This is a prospective cohort study including Peruvian patients with postprandial distress and H. pylori infection confirmed by gastric biopsy who recieved treatment and achieved bacterial eradication. Two years after the initial diagnosis, patients were contacted to determine the recurrence rate of H. pylori infection through the Urea breath test.RESULTS: 101 /129 of the patients that were infected with H. pylori had a successful eradication of the infection and 28/129 failed to eradicate the bacteria. The effectiveness rate of treatment was 77.2%. Two years after successful eradication we were able to contact 65/101 participants, 5 of them presented positive urea breath tests (recurrence rate of infection of 7.7%) (IC 1.5%-13.5%, α = 0.05). The annual recurrence rate was 3.85% per year/ patient. 94% of the patients in the cohort came from poor city areas, 95.4% had drinking water at home and 90.8% drank boiled drinking water on a daily basis.CONCLUSIONS: The recurrence rate of H. pylori in some populations of Peru is lower than expected and comparable with developed countries.

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Recurrencia de la infeccióngástrica con Helicobacter pylori en adultos peruanos con distrés postprandial dos años después de la erradicaciónexitosa

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