TY - JOUR
T1 - Recurrent Respiratory Papillomatosis
AU - Venkatesan, Naren N.
AU - Pine, Harold S.
AU - Underbrink, Michael P.
PY - 2012/6
Y1 - 2012/6
N2 - Recurrent respiratory papillomatosis (RRP) is a rare, benign disease with no known cure. RRP is caused by infection of the upper aerodigestive tract with the human papillomavirus (HPV). Passage through the birth canal is thought to be the initial transmission event, but infection may occur in utero. HPV vaccines have helped to provide protection from cervical cancer; however, their role in the prevention of RRP is undetermined. Clinical presentation of initial symptoms of RRP may be subtle. RRP course varies, and current management focuses on surgical debulking of papillomatous lesions with or without concurrent adjuvant therapy.
AB - Recurrent respiratory papillomatosis (RRP) is a rare, benign disease with no known cure. RRP is caused by infection of the upper aerodigestive tract with the human papillomavirus (HPV). Passage through the birth canal is thought to be the initial transmission event, but infection may occur in utero. HPV vaccines have helped to provide protection from cervical cancer; however, their role in the prevention of RRP is undetermined. Clinical presentation of initial symptoms of RRP may be subtle. RRP course varies, and current management focuses on surgical debulking of papillomatous lesions with or without concurrent adjuvant therapy.
KW - Aerodigestive tract
KW - Human papillomavirus
KW - Papillomas
KW - Papillomatosis
UR - http://www.scopus.com/inward/record.url?scp=84860901729&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84860901729&partnerID=8YFLogxK
U2 - 10.1016/j.otc.2012.03.006
DO - 10.1016/j.otc.2012.03.006
M3 - Review article
C2 - 22588043
AN - SCOPUS:84860901729
SN - 0030-6665
VL - 45
SP - 671
EP - 694
JO - Otolaryngologic Clinics of North America
JF - Otolaryngologic Clinics of North America
IS - 3
ER -