Recurrent Respiratory Papillomatosis

Naren N. Venkatesan, Harold S. Pine, Michael P. Underbrink

Research output: Contribution to journalReview articlepeer-review

95 Scopus citations


Recurrent respiratory papillomatosis (RRP) is a rare, benign disease with no known cure. RRP is caused by infection of the upper aerodigestive tract with the human papillomavirus (HPV). Passage through the birth canal is thought to be the initial transmission event, but infection may occur in utero. HPV vaccines have helped to provide protection from cervical cancer; however, their role in the prevention of RRP is undetermined. Clinical presentation of initial symptoms of RRP may be subtle. RRP course varies, and current management focuses on surgical debulking of papillomatous lesions with or without concurrent adjuvant therapy.

Original languageEnglish (US)
Pages (from-to)671-694
Number of pages24
JournalOtolaryngologic Clinics of North America
Issue number3
StatePublished - Jun 2012


  • Aerodigestive tract
  • Human papillomavirus
  • Papillomas
  • Papillomatosis

ASJC Scopus subject areas

  • Otorhinolaryngology


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