Redox-sensitive Nrf2 and MAPK signaling pathways contribute to trichloroethene-mediated autoimmune disease progression

Keyphrases

• Autoimmune Disease 100%
• Mitogen-activated Protein Kinase 100%
• Trichloroethene 100%
• Disease Progression 100%
• Redox-sensitive 100%
• Nrf2 Signaling Pathway 100%
• Autoimmunity 23%
• Inflammatory Cytokines 15%
• Oxidative Stress 15%
• Interleukin-12 (IL-12) 15%
• Phosphorylation 15%
• Autoimmune Response 15%
• MRL Mouse 15%
• Nuclear Factor Erythroid 2-related Factor 2 (Nrf2) 15%
• MAPK Signaling 15%
• MAPK Inhibitors 15%
• Systemic Lupus Erythematosus 7%
• T Cells 7%
• Molecular Mechanism 7%
• Inducible Nitric Oxide Synthase 7%
• Inflammatory Response 7%
• Liver 7%
• Dysregulation 7%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 7%
• Putative Drug Targets 7%
• Protein Carbonyls 7%
• Nuclear Factor 7%
• NF-B 7%
• In Vivo Applications 7%
• RANTES 7%
• Mechanistic Role 7%
• Liver Proteins 7%
• Every Other Day 7%
• Erythroid 7%
• Human Exposure 7%
• Dichloroacetyl Chloride 7%
• Cytoprotective Genes 7%
• Time Response 7%
• Anti-DNA Antibodies 7%
• Sulforaphane 7%
• Nrf2 Expression 7%
• MAPK p38 7%
• Protein Induction 7%
• Antioxidant Genes 7%
• Nrf2 Signaling 7%

Immunology and Microbiology

• Signal Transduction 100%
• Autoimmune Disease 100%
• Transcription Factor Nrf2 100%
• MAPK Signaling 100%
• Autoimmunity 83%
• Proinflammatory Cytokine 33%
• Oxidative Stress 33%
• Tumor Necrosis Factor 33%
• Metabolite 16%
• Systemic Lupus Erythematosus 16%
• T Cell 16%
• RANTES 16%
• Reaction Time 16%
• Anti-dsDNA Antibodies 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Autoimmune Disease 100%
• Trichloroethylene 100%
• Transcription Factor Nrf2 100%
• Disease Exacerbation 100%
• Cytokine 15%
• Tumor Necrosis Factor 15%
• Disease 7%
• Systemic Lupus Erythematosus 7%
• Cytoprotective Agent 7%
• Antioxidant 7%
• Nuclear Factor 7%
• RANTES 7%
• Liver Protein 7%
• Lead Poisoning 7%
• Sulforaphane 7%