A mutant arylsulfatase B form is described in skin fibroblasts from a patient with Maroteaux-Lamy syndrome. This mutant enzyme is identical in its electrophoretic mobility and antigenic determinants to arylsulfatase B from normal fibroblasts but has a markedly reduced (15%) specific activity.
|Original language||English (US)|
|Number of pages||8|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - Jan 20 1975|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology