Regulation of anabolic and catabolic gene expression in normal and osteoarthritic adult human articular chondrocytes by osteogenic protein-1

Keyphrases

• Gene Expression 100%
• Adult Humans 100%
• Catabolic Genes 100%
• Osteoarthritis 100%
• Osteogenic Proteins 100%
• Human Articular Chondrocytes 100%
• Osteoarthritis Chondrocyte 50%
• Chondrocytes 40%
• Smad 30%
• Recombinant 20%
• Anabolic Effect 20%
• Overexpression 10%
• Intracellular Signaling 10%
• MRNA Level 10%
• Catabolic 10%
• Hyporesponsive 10%
• Expression Level 10%
• Recombinant Human 10%
• High Density 10%
• Cartilage 10%
• Monolayer Culture 10%
• Signaling Mediators 10%
• Matrix-degrading Enzymes 10%
• Matrix metalloproteinase-1 (MMP-1) 10%
• Catabolic Enzymes 10%
• Collagen Type II 10%
• Aggrecan 10%
• Anabolic Factors 10%
• Chondrocyte Metabolism 10%
• Artificial Knee Joint 10%
• ADAMTS-4 10%

Biochemistry, Genetics and Molecular Biology

• Gene Expression 100%
• Synapsin I 100%
• Chondrocyte 100%
• Mediator 18%
• Enzyme 18%
• Metabolic Pathway 9%
• RNA 9%
• Recombinant 9%
• Intracellular Signaling 9%
• mRNA Expression Level 9%
• Monolayer Culture 9%
• Interstitial Collagenase 9%
• Aggrecan 9%
• Type II Collagen 9%
• ADAMTS 9%

Veterinary Science and Veterinary Medicine

• Chondrocyte 100%
• Osteoarthritis 9%